Effectiveness of Messenger RNA Coronavirus Disease 2019 (COVID-19) Vaccines Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in a Cohort of Healthcare Personnel

In a large cohort of United States healthcare personnel without prior coronavirus disease 2019 (COVID-19) infection, 94 382 doses of messenger RNA (mRNA) COVID-19 vaccine were administered to 49 220 individuals. The adjusted vaccine effectiveness following 2 doses of each of the 2 available brands of mRNA vaccine exceeded 96%.

Automated summary

In a large cohort of US healthcare personnel without prior COVID-19 infection, 94,382 doses of mRNA vaccines were administered to 49,220 individuals, with an adjusted vaccine effectiveness exceeding 96% following 2 doses of mRNA vaccine.