4.7 Review

Exhaled breath analysis in disease detection

Journal

CLINICA CHIMICA ACTA
Volume 515, Issue -, Pages 61-72

Publisher

ELSEVIER
DOI: 10.1016/j.cca.2020.12.036

Keywords

Exhaled breath; Volatile organic compounds; Disease diagnosis

Funding

  1. Research Funding for Talents Developing, West China Hospital of Stomatology Sichuan University [RCDWJS2020-4, RCDWJS2020-14]

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The review introduces the conventional and emerging methods for breath analysis in diagnosing and monitoring various diseases. It discusses the correlation between breath components and specific diseases, as well as unique ideas and devices for the diagnosis of common diseases through exhaled breath analysis. The potential application of exhaled breath analysis for diagnosing and screening different diseases is briefly introduced, offering a new avenue for non-invasive disease detection.
Investigating the use of exhaled breath analysis to diagnose and monitor different diseases has attracted much interest in recent years. This review introduces conventionally used methods and some emerging technologies aimed at breath analysis and their relevance to lung disease, airway inflammation, gastrointestinal disorders, metabolic disorders and kidney diseases. One section correlates breath components and specific diseases, whereas the other discusses some unique ideas, strategies, and devices to analyze exhaled breath for the diagnosis of some common diseases. This review aims to briefly introduce the potential application of exhaled breath analysis for the diagnosis and screening of various diseases, thereby providing a new avenue for the detection of non-invasive diseases.

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