4.7 Article

Guideline-Driven Management of Hypertension An Evidence-Based Update

Journal

CIRCULATION RESEARCH
Volume 128, Issue 7, Pages 827-846

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCRESAHA.121.318083

Keywords

American Heart Association; antihypertensive agents; blood pressure; cardiovascular disease; hypertension; mortality

Funding

  1. National Institutes of Health (NIH) [R01-HL-128189, P01-HL-074940]
  2. Ohio Department of Medicaid
  3. Agency for Health Care Research Quality [1U18HS027944-01]
  4. National Institute of General Medical Sciences
  5. Centers of Biomedical Research Excellence award [NIGMS P30-GM-109036]

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This review summarizes important findings on prevention, detection, and management of hypertension since 2017, analyzing research published between 2018 and 2021. The studies cover various aspects including blood pressure measurement, risk assessment, treatment targets, with the potential to increase awareness and control of hypertension.
Several important findings bearing on the prevention, detection, and management of hypertension have been reported since publication of the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline. This review summarizes and places in context the results of relevant observational studies, randomized clinical trials, and meta-analyses published between January 2018 and March 2021. Topics covered include blood pressure measurement, patient evaluation for secondary hypertension, cardiovascular disease risk assessment and blood pressure threshold for drug therapy, lifestyle and pharmacological management, treatment target blood pressure goal, management of hypertension in older adults, diabetes, chronic kidney disease, resistant hypertension, and optimization of care using patient, provider, and health system approaches. Presenting new information in each of these areas has the potential to increase hypertension awareness, treatment, and control which remain essential for the prevention of cardiovascular disease and mortality in the future.

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