4.6 Review

Pneumoconiosis: current status and future prospects

Journal

CHINESE MEDICAL JOURNAL
Volume 134, Issue 8, Pages 898-907

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CM9.0000000000001461

Keywords

Pneumoconiosis; Epidemiology; Diagnosis; Treatment; Emerging technologies

Funding

  1. CAMS Innovation Fund for Medical Sciences (CIFMS) [2018I2M-1-001]
  2. Basic Scientific Research Business Expense Project of Chinese Academy of Medical Sciences [20180709]

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Pneumoconiosis is a spectrum of pulmonary diseases caused by inhaling mineral dust, with chronic inflammation and progressive fibrosis leading to respiratory or heart failure and high mortality. The global threat of pneumoconiosis is attributed to inadequate occupational protection and lack of early diagnostic and effective treatment methods.
Pneumoconiosis refers to a spectrum of pulmonary diseases caused by inhalation of mineral dust, usually as the result of certain occupations. The main pathological features include chronic pulmonary inflammation and progressive pulmonary fibrosis, which can eventually lead to death caused by respiratory and/or heart failure. Pneumoconiosis is widespread globally, seriously threatening global public health. Its high incidence and mortality lie in improper occupational protection, and in the lack of early diagnostic methods and effective treatments. This article reviews the epidemiology, safeguard procedures, diagnosis, and treatment of pneumoconiosis, and summarizes recent research advances and future research prospects.

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