Journal
CHINESE CHEMICAL LETTERS
Volume 32, Issue 11, Pages 3514-3517Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2021.04.037
Keywords
C-H Functionalization; Enaminone; Perfluoroalkyl sulfonylation; Metal-free; Configuration inversion
Categories
Funding
- National Natural Science Foundation of China [21861019]
- Natural Science Foundation of Jiangxi Province [20202ACBL203006]
Ask authors/readers for more resources
The perfluoroalkylsulfonylation in enaminone C-H bonds has been achieved by using molecular iodine promotion and stable, inexpensive sodium perfluoroalkyl sulfinates as coupling partners, leading to the stereoselective synthesis of E-configurated alpha-perfluoroalkylsulfonyl enaminones.
The perfluoroalkylsulfonylation (CF3SO2, C2F5SO2 and CHF2SO2) in the enaminone C-H bonds has been developed simply via the promotion of molecular iodine by using stable and cheap sodium perfluoroalkyl sulfinates as coupling partners. The stereoselective synthesis of E-configurated alpha-perfluoroalkylsulfonyl enaminones has been realized via unprecedented C-H bond elaboration and C= C double bond configuration inversion by free radical process. (C) 2021 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
