Uncommon Four-Membered Building Blocks - Cyclobutenes, Azetines and Thietes

Strained ring systems have gained considerable importance over the last few years for their implication in natural product syntheses or in drug discovery programs. We present herein a recollection of our work on the construction and functionalization of unsaturated four-membered carbo- and heterocycles in the context of the literature, as well as their applications in further reactions.

Automated summary

Strained ring systems have become increasingly important in natural product syntheses and drug discovery programs in recent years. Our work focuses on the construction and functionalization of unsaturated four-membered carbo- and heterocycles, as well as their applications in further reactions.