Journal
CERAMICS INTERNATIONAL
Volume 47, Issue 14, Pages 19727-19736Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ceramint.2021.03.311
Keywords
Nevirapine; Cubic clover-like faces nanostructures; Eu3+/Cu2O nanostructure; Voltammtry
Categories
Funding
- Research Councils of Islamic Azad University of Kerman
- Islamic Azad University of Kerman
Ask authors/readers for more resources
In this experiment, a three-dimensional cubic structure of europium (Eu) (3+)/cuprous oxide (Cu2O) with clover-like face-centered nanostructures was successfully synthesized for the determination of nevirapine using electrochemical methods. The synergistic influence of the Eu3+/Cu2O CLFNs enhanced the electrocatalytic capability of the electrode and raised the active site. Various techniques were employed to analyze the modified electrode, and it was found to be effective for the determination of nevirapine.
In this experiment, an original three-dimensional (3D) cubic of europium (Eu) (3+)/cuprous oxide (Cu2O) with clover-like face-centered nanostructures (Eu3+/Cu2O CLFNs) was successfully synthesized to determine nevirapine (C15H14N4O), using electrochemical methods. The surface morphology of the Ns was correspondingly identified through different techniques, including energy dispersive X-ray spectroscopy (EDX), X-ray powder diffraction (XRD), and scanning electron microscopy (SEM). In this sense, the synergistic influence of the Eu3+/Cu2O CLFNs enhanced the electrocatalytic capability of the electrode via a modified glassy carbon (GC) and raised the active site. Employing various approaches, the modified electrode was then analyzed through cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Moreover, kinetic parameters and electrochemical ones were estimated by means of voltammetric methods. For the determination of nevirapine applying the Eu3+/Cu2O CLFNs/GC electrode (GCE), differential pulse voltammetry (DPV) was further utilized. Under optimized conditions, the range of linear responses was between 0.01 and 750.0 mu M with the limit of detection (LOD) of 3.6 nM, whereas the recommended sensor sensitivity was equal to 0.1244 mu A/mu M. The response time of approximately 3.5 min and the reproducibility (inter-and intra-electrode reproducibility of 2.26% and 1.51%, respectively) were subsequently achieved. It was concluded that sensors have been thus far exploited to determine nevirapine in real samples with favorable outcomes, indicating that electrocatalysis modifier can be assumed as one of appropriate catalysts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available