Recent advances in liposome formulations for breast cancer therapeutics

Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we discuss liposome design with the targeting feature and triggering functions. We also summarise the recent progress (since 2014) in liposome-based therapeutics for breast cancer including chemotherapy and gene therapy. We finally identify some challenges on the liposome technology development for the future clinical translation.

Automated summary

Liposomes, among various nanoparticle-based delivery platforms, have shown particular success in clinical applications, especially in cancer therapy like breast cancer. This review discusses liposome design with targeting and triggering functions, as well as recent advancements in liposome-based therapeutics for breast cancer since 2014. Challenges in the future clinical translation of liposome technology are also identified.