Related references
Note: Only part of the references are listed.Homeobox proteins are essential for fungal differentiation and secondary metabolism in Aspergillus nidulans
Sung-Hun Son et al.
SCIENTIFIC REPORTS (2020)
PITX3 mutations associated with autosomal dominant congenital cataract in the Chinese population
Zehua Wu et al.
MOLECULAR MEDICINE REPORTS (2019)
PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
Jing Luo et al.
CANCER CELL INTERNATIONAL (2019)
Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation
Min Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Requirement of Pitx2 for skeletal muscle homeostasis
Chih-Ning Chang et al.
DEVELOPMENTAL BIOLOGY (2019)
PITX2 methylation: a novel and effective biomarker for monitoring biochemical recurrence risk of prostate cancer
Qi Jiang et al.
MEDICINE (2019)
Significance of PITX2 Promoter Methylation in Colorectal Carcinoma Prognosis
Alexander Semaan et al.
CLINICAL COLORECTAL CANCER (2018)
PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets
Jialiang S. Wang et al.
DEVELOPMENTAL BIOLOGY (2018)
The role of homeodomain transcription factors in fungal development
Peter Jan Vonk et al.
FUNGAL BIOLOGY REVIEWS (2018)
Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition
Lele Li et al.
DEVELOPMENT (2018)
The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration
Aurore L'honore et al.
ELIFE (2018)
Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma
Meredith E. Protas et al.
HUMAN MOLECULAR GENETICS (2017)
PITX2 DNA Methylation as Biomarker for Individualized Risk Assessment of Prostate Cancer in Core Biopsies
Barbara Uhl et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2017)
Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation
Jinjin Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cerberus-Nodal-Lefty-Pitx signaling cascade controls left-right asymmetry in amphioxus
Guang Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Left-Right Patterning: Breaking Symmetry to Asymmetric Morphogenesis
Daniel T. Grimes et al.
TRENDS IN GENETICS (2017)
Hedgehog participates in the establishment of left-right asymmetry during amphioxus development by controlling Cerberus expression
Guangwei Hu et al.
DEVELOPMENT (2017)
Multiple Roles of Pitx2 in Cardiac Development and Disease
Diego Franco et al.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2017)
Pitx1 directly modulates the core limb development program to implement hindlimb identity
Stephen Nemec et al.
DEVELOPMENT (2017)
PITX2 loss-of-function mutation contributes to tetralogy of Fallot
Yu-Min Sun et al.
GENE (2016)
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury
Ge Tao et al.
NATURE (2016)
Mapping the chromatin state dynamics in myoblasts
Arun J. Singh et al.
GENE REPORTS (2016)
Current Perspectives in Cardiac Laterality
Marina Campione et al.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2016)
A Pitx2-MicroRNA Pathway Modulates Cell Proliferation in Myoblasts and Skeletal-Muscle Satellite Cells and Promotes Their Commitment to a Myogenic Cell Fate
Estefana Lozano-Velasco et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Invasion of ovarian cancer cells is induced byPITX2-mediated activation of TGF-β and Activin-A
Moitri Basu et al.
MOLECULAR CANCER (2015)
Chromatin Architecture of the Pitx2 Locus Requires CTCF- and Pitx2-Dependent Asymmetry that Mirrors Embryonic Gut Laterality
Ian C. Welsh et al.
CELL REPORTS (2015)
PITX2 Loss-of-Function Mutation Contributes to Congenital Endocardial Cushion Defect and Axenfeld-Rieger Syndrome
Cui-Mei Zhao et al.
PLOS ONE (2015)
Pitx2, an Atrial Fibrillation Predisposition Gene, Directly Regulates Ion Transport and Intercalated Disc Genes
Ye Tao et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2014)
PITX2C loss-of-function mutations responsible for idiopathic atrial fibrillation
Xing-Biao Qiu et al.
CLINICS (2014)
Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb
Hidetaka Shiratori et al.
DEVELOPMENTAL BIOLOGY (2014)
The Left-Right Pitx2 Pathway Drives Organ-Specific Arterial and Lymphatic Development in the Intestine
Aparna Mahadevan et al.
DEVELOPMENTAL CELL (2014)
Redox Regulation by Pitx2 and Pitx3 Is Critical for Fetal Myogenesis
Aurore L'honore et al.
DEVELOPMENTAL CELL (2014)
Novel PITX2c loss-of-function mutations associated with complex congenital heart disease
Dong Wei et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2014)
Nodal signalling determines biradial asymmetry in Hydra
Hiroshi Watanabe et al.
NATURE (2014)
Novel and recurrent PITX3 mutations in Belgian families with autosomal dominant congenital cataract and anterior segment dysgenesis have similar phenotypic and functional characteristics
Hannah Verdin et al.
ORPHANET JOURNAL OF RARE DISEASES (2014)
Roles of cilia, fluid flow, and Ca2+ signaling in breaking of left-right symmetry
Satoko Yoshiba et al.
TRENDS IN GENETICS (2014)
Pitx genes are redeployed in adult myogenesis where they can act to promote myogenic differentiation in muscle satellite cells
Paul Knopp et al.
DEVELOPMENTAL BIOLOGY (2013)
Pitx2-Mediated Cardiac Outflow Tract Remodeling
Hsiao-Yen Ma et al.
DEVELOPMENTAL DYNAMICS (2013)
Prevalence and Spectrum of PITX2c Mutations Associated with Congenital Heart Disease
Juan Wang et al.
DNA AND CELL BIOLOGY (2013)
Liebenberg syndrome is caused by a deletion upstream to the PITX1 gene resulting in transformation of the upper limbs to reflect lower limb characteristics
Mohammad M. Al-Qattan et al.
GENE (2013)
PITX2: A promising predictive biomarker of patients' prognosis and chemoradioresistance in esophageal squamous cell carcinoma
Jia-Xing Zhang et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
PITX2c Loss-of-Function Mutations Responsible for Congenital Atrial Septal Defects
Fang Yuan et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2013)
Wnt/β-Catenin Pathway Is Regulated by PITX2 Homeodomain Protein and Thus Contributes to the Proliferation of Human Ovarian Adenocarcinoma Cell, SKOV-3
Moitri Basu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Cyclin A1 is a transcriptional target of PITX2 and overexpressed in papillary thyroid carcinoma
Yan Liu et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2013)
Association of PITX2 mRNA down-regulation in prostate cancer with promoter hypermethylation and poor prognosis
Anna Vinarskaja et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2013)
Pitx2 confers left morphological, molecular, and functional identity to the sinus venosus myocardium
Grazia Ammirabile et al.
CARDIOVASCULAR RESEARCH (2012)
DNA Methylation of the Homeobox Genes PITX2 and SHOX2 Predicts Outcome in Non-small-cell Lung Cancer Patients
Dimo Dietrich et al.
DIAGNOSTIC MOLECULAR PATHOLOGY (2012)
PITX2 and FOXC1 spectrum of mutations in ocular syndromes
Linda M. Reis et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2012)
Prediction of gene network models in limb muscle precursors
Adam L. Campbell et al.
GENE (2012)
A novel TaulacZ allele reveals a requirement for Pitx2 in formation of the mammillothalamic tract
Jennifer M. Skidmore et al.
GENESIS (2012)
Regulation of Motility of Myogenic Cells in Filling Limb Muscle Anlagen by Pitx2
Adam L. Campbell et al.
PLOS ONE (2012)
Increased Expression of PITX2 Transcription Factor Contributes to Ovarian Cancer Progression
Frederic K. C. Fung et al.
PLOS ONE (2012)
Pax6: A multi-level regulator of ocular development
Ohad Shaham et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2012)
The Significance of PITX2 Overexpression in Human Colorectal Cancer
Hajime Hirose et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
PITX2 Insufficiency Leads to Atrial Electrical and Structural Remodeling Linked to Arrhythmogenesis
Ana Chinchilla et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2011)
Genetics of anterior segment dysgenesis disorders
Linda M. Reis et al.
CURRENT OPINION IN OPHTHALMOLOGY (2011)
Pitx1 is necessary for normal initiation of hindlimb outgrowth through regulation of Tbx4 expression and shapes hindlimb morphologies via targeted growth control
Veronique Duboc et al.
DEVELOPMENT (2011)
Pitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice
David M. Alvarado et al.
HUMAN MOLECULAR GENETICS (2011)
ASSOCIATION FOR ACADEMIC SURGERY Pitx2 is a Critical Early Regulatory Gene in Normal Cecal Development
Peter F. Nichol et al.
JOURNAL OF SURGICAL RESEARCH (2011)
PITX2 AND PITX1 Regulate Thyrotroph Function and Response to Hypothyroidism
F. Castinetti et al.
MOLECULAR ENDOCRINOLOGY (2011)
Pituitary homeobox 2 (PITX2) promotes thyroid carcinogenesis by activation of cyclin D2
Yue Huang et al.
CELL CYCLE (2010)
Pitx2 defines alternate pathways acting through MyoD during limb and somitic myogenesis
Aurore L'Honore et al.
DEVELOPMENT (2010)
Case of novel PITX2 gene mutation associated with Peters' anomaly and persistent hyperplastic primary vitreous
A. Arikawa et al.
EYE (2010)
Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification
Jun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A Comprehensive Classification and Evolutionary Analysis of Plant Homeobox Genes
Krishanu Mukherjee et al.
MOLECULAR BIOLOGY AND EVOLUTION (2009)
Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells
Hsin-Yi Ho et al.
MECHANISMS OF DEVELOPMENT (2009)
A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity
Laskaro Zagoraiou et al.
NEURON (2009)
An Altered Phenotype in a Conditional Knockout of Pitx2 in Extraocular Muscle
Yuefang Zhou et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Asymmetric Lower-Limb Malformations in Individuals with Homeobox PITX1 Gene Mutation
Christina A. Gurnett et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Novel forms of Paired-like homeodomain transcription factor 2 (PITX2):: Generation by alternative translation initiation and mRNA splicing
Pankaj Lamba et al.
BMC MOLECULAR BIOLOGY (2008)
Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes
Thimios A. Mitsiadis et al.
DEVELOPMENTAL BIOLOGY (2008)
Independent and dynamic reallocation of pitx gene expression during vertebrate evolution, with emphasis on fish pituitary development
Anna R. Angotzi et al.
GENE (2008)
Pitx2 Deletion in Pituitary Gonadotropes is Compatible With Gonadal Development, Puberty, and Fertility
Michael A. Charles et al.
GENESIS (2008)
The Trichoplax genome and the nature of placozoans
Mansi Srivastava et al.
NATURE (2008)
The direction of gut looping is established by changes in the extracellular matrix and in cell:cell adhesion
Natasza A. Kurpios et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Classification and nomenclature of all human homeobox genes
Peter W. H. Holland et al.
BMC BIOLOGY (2007)
Pitx2c and nkx2-5 are required for the formation and identity of the pulmonary myocardium
Mathilda T. M. Mommersteeg et al.
CIRCULATION RESEARCH (2007)
Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development
Aurore L'Honore et al.
DEVELOPMENTAL BIOLOGY (2007)
Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch
Hung Ping Shih et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Nodal signaling: developmental roles and regulation
Michael M. Shen
DEVELOPMENT (2007)
Expression pattern of the homeodomain transcription factor Pitx2 during muscle development
Hung Ping Shih et al.
GENE EXPRESSION PATTERNS (2007)
Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb
April DeLaurier et al.
DEVELOPMENTAL BIOLOGY (2006)
Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium
Di Ai et al.
DEVELOPMENTAL BIOLOGY (2006)
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype
C Martinat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Expression of Pitx2 in stromal cells is required for normal hematopoiesis
A Kieusseian et al.
BLOOD (2006)
Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development
AL Evans et al.
HUMAN MOLECULAR GENETICS (2005)
PITX genes are required for cell survival and Lhx3 activation
MA Charles et al.
MOLECULAR ENDOCRINOLOGY (2005)
Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons
SL Zhao et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain
DM Martin et al.
DEVELOPMENTAL BIOLOGY (2004)
Mutation in PITX2 is associated with ring dermoid of the cornea -: art. no. e129
K Xia et al.
JOURNAL OF MEDICAL GENETICS (2004)
Is SHORT syndrome another phenotypic variation of PITX2?
NN Karadeniz et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2004)
The Wnt/β-catenin→Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs
P Briata et al.
MOLECULAR CELL (2003)
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons
P van den Munckhof et al.
DEVELOPMENT (2003)
Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois
LA Naiche et al.
DEVELOPMENT (2003)
Pitx3 is required for development of substantia nigra dopaminergic neurons
I Nunes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway
SH Baek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration
W Liu et al.
DEVELOPMENT (2003)
The Arabidopsis homeobox gene, ATHB16, regulates leaf development and the sensitivity to photoperiod in Arabidopsis
Y Wang et al.
DEVELOPMENTAL BIOLOGY (2003)
Identification of a Wnt/DVI/β-catenin → Pitx2 pathway mediating cell-type-specific proliferation during development
C Kioussi et al.
CELL (2002)
A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent development of Arabidopsis flowers
N Matsumoto et al.
GENES & DEVELOPMENT (2001)
Nodal signalling in vertebrate development
AF Schier et al.
NATURE (2000)