4.4 Review

Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease

Related references

Note: Only part of the references are listed.
Article Physiology

IL-4/IL-13 upregulates Sonic hedgehog expression to induce allergic airway epithelial remodeling

Xiangzhi Wang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2020)

Review Biochemistry & Molecular Biology

Noncanonical Wnt planar cell polarity signaling in lung development and disease

Eszter K. Vladar et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2020)

Article Medicine, General & Internal

Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

Randa Belgacemi et al.

EBIOMEDICINE (2020)

Article Multidisciplinary Sciences

Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

Katherine C. Goldfarbmuren et al.

NATURE COMMUNICATIONS (2020)

Review Genetics & Heredity

FGF Signaling in Lung Development and Disease: Human Versus Mouse

Soula Danopoulos et al.

FRONTIERS IN GENETICS (2019)

Article Multidisciplinary Sciences

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair

Hyun-Taek Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Respiratory System

Risk factors for diagnostic delay in idiopathic pulmonary fibrosis

Nils Hoyer et al.

RESPIRATORY RESEARCH (2019)

Article Biochemistry & Molecular Biology

Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naive and Mucoobstructed Mice

Gang Chen et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)

Review Multidisciplinary Sciences

Diverse mechanisms for endogenous regeneration and repair in mammalian organs

James M. Wells et al.

NATURE (2018)

Article Multidisciplinary Sciences

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

Lindsey W. Plasschaert et al.

NATURE (2018)

Article Multidisciplinary Sciences

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Daniel T. Montoro et al.

NATURE (2018)

Article Otorhinolaryngology

Nasal polyp fibroblasts modulate epithelial characteristics via Wnt signaling

Alex Dobzanski et al.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2018)

Review Genetics & Heredity

Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury

Tingting Yuan et al.

FRONTIERS IN GENETICS (2018)

Review Cell Biology

Mucins and Their Role in Shaping the Functions of Mucus Barriers

C. E. Wagner et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)

Article Anatomy & Morphology

Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia

Dingyuan I. Sun et al.

CELLS TISSUES ORGANS (2018)

Article Oncology

Motile and non-motile cilia in human pathology: from function to phenotypes

Hannah M. Mitchison et al.

JOURNAL OF PATHOLOGY (2017)

Review Biochemistry & Molecular Biology

Dynamic chromatin regulation at Notch target genes

Benedetto Daniele Giaimo et al.

TRANSCRIPTION-AUSTIN (2017)

Article Medicine, Research & Experimental

Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways

Lubna H. Abdullah et al.

JCI INSIGHT (2017)

Review Microbiology

The Interaction between Respiratory Pathogens and Mucus

Mark Zanin et al.

CELL HOST & MICROBE (2016)

Article Cell & Tissue Engineering

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

Hongmei Mou et al.

CELL STEM CELL (2016)

Article Surgery

The role and importance of club cells (Clara cells) in the pathogenesis of some respiratory diseases

Wojciech Rokicki et al.

KARDIOCHIRURGIA I TORAKOCHIRURGIA POLSKA (2016)

Review Cell Biology

Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style

Allyson J. Merrell et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)

Article Cell Biology

Multiciliated Cells in Animals

Alice Meunier et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Article Respiratory System

WNT Signaling in Lung Aging and Disease

Mareike Lehmann et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2016)

Review Physiology

Cilia Dysfunction in Lung Disease

Ann E. Tilley et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 77 (2015)

Review Biochemistry & Molecular Biology

Mucins: A biologically relevant glycan barrier in mucosal protection

Anthony P. Corfield

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)

Review Genetics & Heredity

From big data analysis to personalized medicine for all: challenges and opportunities

Akram Alyass et al.

BMC MEDICAL GENOMICS (2015)

Article Developmental Biology

BMP signalling controls the construction of vertebrate mucociliary epithelia

Marie Cibois et al.

DEVELOPMENT (2015)

Article Multidisciplinary Sciences

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

Daniel Lafkas et al.

NATURE (2015)

Article Multidisciplinary Sciences

Parent stem cells can serve as niches for their daughter cells

Ana Pardo-Saganta et al.

NATURE (2015)

Article Biochemical Research Methods

The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells

Sarah X. L. Huang et al.

NATURE PROTOCOLS (2015)

Article Multidisciplinary Sciences

p63+Krt5+ distal airway stem cells are essential for lung regeneration

Wei Zuo et al.

NATURE (2015)

Article Multidisciplinary Sciences

Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface

Andrea C. Schamberger et al.

SCIENTIFIC REPORTS (2015)

Article Physiology

Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells

Korbinian Ballweg et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

Article Physiology

Sox2 modulates Lef-1 expression during airway submucosal gland development

Weiliang Xie et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

Article Biochemistry & Molecular Biology

Cigarette Smoke-Induced Disruption of Bronchial Epithelial Tight Junctions Is Prevented by Transforming Growth Factor-β

Andrea C. Schamberger et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)

Review Biochemistry & Molecular Biology

Multiciliated Cells

Eric R. Brooks et al.

CURRENT BIOLOGY (2014)

Article Cell Biology

Polarized Wnt Signaling Regulates Ectodermal Cell Fate in Xenopus

Ya-Lin Huang et al.

DEVELOPMENTAL CELL (2014)

Article Biotechnology & Applied Microbiology

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

Sarah X. L. Huang et al.

NATURE BIOTECHNOLOGY (2014)

Article Multidisciplinary Sciences

deltaNp63 Has a Role in Maintaining Epithelial Integrity in Airway Epithelium

Ari Jon Arason et al.

PLOS ONE (2014)

Article Biochemistry & Molecular Biology

Ciliated Cells of Pseudostratified Airway Epithelium Do Not Become Mucous Cells after Ovalbumin Challenge

Ana Pardo-Saganta et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Dedifferentiation of committed epithelial cells into stem cells in vivo

Purushothama Rao Tata et al.

NATURE (2013)

Review Cell Biology

Recent advances and contraversies on the role of pulmonary neuroepithelial bodies as airway sensors

Ernest Cutz et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2013)

Article Multidisciplinary Sciences

Cigarette Smoking Decreases Global MicroRNA Expression in Human Alveolar Macrophages

Joel W. Graff et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

Daniel Ambort et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cell Biology

Signaling Mechanisms Controlling Cell Fate and Embryonic Patterning

Norbert Perrimon et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Review Public, Environmental & Occupational Health

Environmental Determinants of Chronic Disease and Medical Approaches: Recognition, Avoidance, Supportive Therapy, and Detoxification

Margaret E. Sears et al.

JOURNAL OF ENVIRONMENTAL AND PUBLIC HEALTH (2012)

Article Biochemistry & Molecular Biology

Goblet Cells Are Derived from a FOXJ1-Expressing Progenitor in a Human Airway Epithelium

Jonathan Turner et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)

Editorial Material Biochemistry & Molecular Biology

SnapShot: BMP Signaling in Development

James A. Dutko et al.

Article Cell & Tissue Engineering

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

Jason R. Rock et al.

CELL STEM CELL (2011)

Article Developmental Biology

Specification of ion transport cells in the Xenopus larval skin

Ian K. Quigley et al.

DEVELOPMENT (2011)

Article Allergy

Gene-environment interaction in chronic disease: A European Science Foundation Forward Look

Harald Renz et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)

Article Cell Biology

Dystroglycan is involved in skin morphogenesis downstream of the Notch signaling pathway

Cathy Sirour et al.

MOLECULAR BIOLOGY OF THE CELL (2011)

Article Biochemistry & Molecular Biology

Interleukin-13 Induces Mucin 5AC Production Involving STAT6/SPDEF in Human Airway Epithelial Cells

Hongmei Yu et al.

CELL COMMUNICATION AND ADHESION (2010)

Article Cell Biology

Planar cell polarity signaling, cilia and polarized ciliary beating

John B. Wallingford

CURRENT OPINION IN CELL BIOLOGY (2010)

Review Cell Biology

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

Jason R. Rock et al.

DISEASE MODELS & MECHANISMS (2010)

Article Biochemistry & Molecular Biology

Clara cell: Progenitor for the bronchiolar epithelium

Susan D. Reynolds et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)

Review Medicine, General & Internal

MEDICAL PROGRESS Airway Mucus Function and Dysfunction

John V. Fahy et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Pharmacology & Pharmacy

Unraveling human complexity and disease with systems biology and personalized medicine

Stephen Naylor et al.

PERSONALIZED MEDICINE (2010)

Article Critical Care Medicine

Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease

Ann E. Tilley et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)

Article Biochemistry & Molecular Biology

β-Catenin Is Not Necessary for Maintenance or Repair of the Bronchiolar Epithelium

Anna C. Zemke et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

The motile cilium in development and disease: emerging new insights

Sudipto Roy

BIOESSAYS (2009)

Article Developmental Biology

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

J. Sawalla Guseh et al.

DEVELOPMENT (2009)

Article Medicine, Research & Experimental

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

Gang Chen et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Multidisciplinary Sciences

Basal cells as stem cells of the mouse trachea and human airway epithelium

Jason R. Rock et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cell & Tissue Engineering

Conditional stabilization of β-catenin expands the pool of lung stem cells

Susan D. Reynolds et al.

STEM CELLS (2008)

Article Cell Biology

Dishevelled links basal body docking and orientation in ciliated epithelial cells

Eszter K. Vladar et al.

TRENDS IN CELL BIOLOGY (2008)

Review Endocrinology & Metabolism

Uteroglobin:: a steroid-inducible immunomodulatory protein that founded the Secretoglobin superfamily

Anil B. Mukherjee et al.

ENDOCRINE REVIEWS (2007)

Article Biochemistry & Molecular Biology

IL-13 regulates cilia loss and foxj1 expression in human airway epithelium

Brigitte N. Gomperts et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

p63 is essential for the proliferative potential of stem cells in stratified epithelia

Makoto Senoo et al.

Article Developmental Biology

Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis

Ryan R. Driskell et al.

DEVELOPMENTAL BIOLOGY (2007)

Article Developmental Biology

Radial intercalation of ciliated cells during Xenopus skin development

Jennifer L. Stubbs et al.

DEVELOPMENT (2006)

Review Biochemistry & Molecular Biology

Airway mucus - From production to secretion

OW Williams et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)

Article Medicine, Research & Experimental

Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals

JW Tyner et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Physiology

β-Catenin regulates differentiation of respiratory epithelial cells in vivo

ML Mucenski et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

Article Biochemistry & Molecular Biology

Mucin is produced by Clara cells in the proximal airways of antigen-challenged mice

CM Evans et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2004)

Article Physiology

Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis

RR Driskell et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)

Article Cell Biology

Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium

Y Daniely et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)

Article Biochemistry & Molecular Biology

To beat or not to beat:: roles of cilia in development and disease

I Ibañez-Tallon et al.

HUMAN MOLECULAR GENETICS (2003)