4.8 Editorial Material

New scavenger to fine-tune insulin action in β cells

Journal

CELL METABOLISM
Volume 33, Issue 4, Pages 707-708

Publisher

CELL PRESS
DOI: 10.1016/j.cmet.2021.03.013

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Funding

  1. Alice Bohmfalk Charitable Trust Award
  2. Columbia University Diabetes Research Center Pilot and Feasibility (PF) grants

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The study identified a new insulin inhibitory receptor, inceptor, which balances insulin signaling by promoting insulin receptor internalization, playing a crucial role in maintaining beta cell homeostasis.
Insulin receptor signaling is crucial for beta cell homeostasis. In a recent issue of Nature, Ansarullah et al. (2021) have identified the insulin inhibitory receptor (inceptor), which balances insulin signaling by promoting insulin receptor internalization.

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