Journal
CELL CALCIUM
Volume 95, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ceca.2021.102371
Keywords
Orai1; STIM1; Light-operated Ca2+ channel
Categories
Funding
- National Institute of Health [AI083432, AI146615, AI146352]
Ask authors/readers for more resources
Researchers have successfully developed a novel light-operated Ca2+ channel that can selectively and efficiently elevate cytoplasmic Ca2+ levels.
The current optogenetic tools to elevate cytoplasmic Ca2+ concentrations either do not have high ion selectivity or activate undesirable signaling pathways. He et al. (2021) generated a light-operated Ca2+ channel by integrating a photosensitive module directly into ORAI1 channels to selectively raise cytoplasmic Ca2+ levels.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
