4.3 Review

Trimethylamine/Trimethylamine-N-Oxide as a Key Between Diet and Cardiovascular Diseases

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Vascular reactivity stimulated by TMA and TMAO: Are perivascular adipose tissue and endothelium involved?

Carolina Baraldi A. Restini et al.

Summary: Trimethylamine and Trimethylamine-N-Oxide may directly affect vascular tone, with the former causing greater arterial constriction than the latter. Perivascular adipose tissue and endothelium play regulatory roles in this process.

PHARMACOLOGICAL RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies

Wan-Qin Zhang et al.

Summary: Hypertension, as the most prevalent chronic disease and risk factor for various diseases, has been linked with novel gut microbiota and its metabolites, suggesting potential new interventions for treatment. Further research is needed to explore the relationship between hypertension and TMA/TMAO for clinical applications.

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2021)

Article Geriatrics & Gerontology

Trimethylamine But Not Trimethylamine Oxide Increases With Age in Rat Plasma and Affects Smooth Muscle Cells Viability

Kinga Jaworska et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Review Pharmacology & Pharmacy

Metabolic endotoxemia and cardiovascular disease: A systematic review about potential roles of prebiotics and probiotics

Jalal Moludi et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2020)

Review Nutrition & Dietetics

Trimethylamine N-Oxide in Relation to Cardiometabolic Health-Cause or Effect?

Christopher Papandreou et al.

NUTRIENTS (2020)

Review Pharmacology & Pharmacy

Targeting the human microbiome and its metabolite TMAO in cardiovascular prevention and therapy

Lisa Dannenberg et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Review Medicine, Research & Experimental

A critical review on the relationship of herbal medicine, Akkermansia muciniphila, and human health

Fan Bu et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Medicine, Research & Experimental

Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

Zehua Li et al.

LABORATORY INVESTIGATION (2019)

Review Cardiac & Cardiovascular Systems

Intestinal Microbiota in Cardiovascular Health and Disease

W. H. Wilson Tang et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Article Biochemistry & Molecular Biology

Trimethylamine N-Oxide Does Not Impact Viability, ROS Production, and Mitochondrial Membrane Potential of Adult Rat Cardiomyocytes

Giulia Querio et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction

Gurinder Bir Singh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Clinical Neurology

Gut Microbiota and Ischemic Stroke: The Role of Trimethylamine N-Oxide

Hyo Suk Nam

JOURNAL OF STROKE (2019)

Article Food Science & Technology

TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology

Kinga Jaworska et al.

TOXINS (2019)

Review Cardiac & Cardiovascular Systems

Role and Effective Therapeutic Target of Gut Microbiota in Heart Failure

Qiujin Jia et al.

CARDIOVASCULAR THERAPEUTICS (2019)

Review Biochemistry & Molecular Biology

Role and mechanism of ROS scavengers in alleviating NLRP3-mediated inflammation

Takami Sho et al.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2019)

Article Cardiac & Cardiovascular Systems

Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients With Decompensated and Compensated Heart Failure

Tomohiro Hayashi et al.

CIRCULATION JOURNAL (2019)

Article Medicine, Research & Experimental

Trimethylamine-N-oxide, as a risk factor for atherosclerosis, induces stress in J774A.1 murine macrophages

Abbas Mohammadi et al.

ADVANCES IN MEDICAL SCIENCES (2018)

Article Medicine, Research & Experimental

Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway

Jin Geng et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Cardiac & Cardiovascular Systems

Metabolic Biomarkers in Heart Failure

Chonyang L. Albert et al.

HEART FAILURE CLINICS (2018)

Article Cardiac & Cardiovascular Systems

Chronic, low-dose TMAO treatment reduces diastolic dysfunction and heart fibrosis in hypertensive rats

Tomasz Huc et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)

Article Biochemistry & Molecular Biology

Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential

Adam B. Roberts et al.

NATURE MEDICINE (2018)

Review Pharmacology & Pharmacy

The Role of Gut Microbiota in Atherosclerosis and Hypertension

Junli Ma et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Type-2 diabetes mellitus and cardiovascular disease

Robert J. Henning

FUTURE CARDIOLOGY (2018)

Article Medical Laboratory Technology

Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction

Toru Suzuki et al.

CLINICAL CHEMISTRY (2017)

Review Cardiac & Cardiovascular Systems

Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

Gabriele Giacomo Schiattarella et al.

EUROPEAN HEART JOURNAL (2017)

Article Toxicology

Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria

Marina Makrecka-Kuka et al.

TOXICOLOGY LETTERS (2017)

Article Multidisciplinary Sciences

The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie et al.

NATURE COMMUNICATIONS (2017)

Article Nutrition & Dietetics

Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes

Zhilei Shan et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2017)

Article Cell Biology

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

Krishna M. Boini et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome

Xiaolei Sun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Weifei Zhu et al.

Article Endocrinology & Metabolism

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels

M. Dambrova et al.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2016)

Review Biochemistry & Molecular Biology

The complex metabolism of trimethylamine in humans: endogenous and exogenous sources

Jyoti Chhibber-Goel et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2016)

Article Cardiac & Cardiovascular Systems

Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction

Susanne H. Karbach et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Article Multidisciplinary Sciences

Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans

Elko Randrianarisoa et al.

SCIENTIFIC REPORTS (2016)

Review Nutrition & Dietetics

TMAO: A small molecule of great expectations

Marcin Ufnal et al.

NUTRITION (2015)

Review Biochemistry & Molecular Biology

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

Daniela Senft et al.

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Article Multidisciplinary Sciences

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

Ji Miao et al.

NATURE COMMUNICATIONS (2015)

Article Nutrition & Dietetics

The Mediterranean-style dietary pattern and mortality among men and women with cardiovascular disease

Esther Lopez-Garcia et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2014)

Article Cardiac & Cardiovascular Systems

Trimethylamine-N-Oxide: A Carnitine-Derived Metabolite That Prolongs the Hypertensive Effect of Angiotensin II in Rats

Marcin Ufnal et al.

CANADIAN JOURNAL OF CARDIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

Xiang Gao et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2014)

Article Cardiac & Cardiovascular Systems

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure Refining the Gut Hypothesis

W. H. Wilson Tang et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Article Multidisciplinary Sciences

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

Yijun Zhu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biochemistry & Molecular Biology

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

Robert A. Koeth et al.

NATURE MEDICINE (2013)

Article Multidisciplinary Sciences

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang et al.

NATURE (2011)

Article Biophysics

G protein-coupled receptor mediated trimethylamine sensing

Anke Suska et al.

BIOSENSORS & BIOELECTRONICS (2009)

Review Peripheral Vascular Disease

Role of angiotensin II in cardiovascular disease - Therapeutic implications of more than a century of research

CM Ferrario

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2006)