Journal
CANCER CELL
Volume 39, Issue 4, Pages 463-465Publisher
CELL PRESS
DOI: 10.1016/j.ccell.2021.03.005
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Funding
- Human Frontier Scientific Program [RGY0071/2018]
- Suh Kyungbae Foundation [SUHF18010082]
- National Research Foundation of Korea (NRF) - Korean Government [NRF-2020R1A3B2078973]
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The study utilizes sophisticated statistical analyses on population-scale cancer whole-genome sequences to characterize the genomic architecture of intratumor heterogeneity, providing unprecedented insights into subclones in about 30 cancer types.
Using sophisticated statistical analyses on population-scale cancer whole-genome sequences, a new study published in Cell characterizes the genomic architecture of intratumor heterogeneity (ITH). It results in an unprecedented snapshot of subclones in about 30 cancer types, generating a wealth of insight into the underlying mutational events, processes, and their selection.
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