4.7 Article

Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

Improving drug response prediction by integrating multiple data sources: matrix factorization, kernel and network-based approaches

Betul Guvenc Paltun et al.

Summary: Predicting the response of cancer cell lines to specific drugs is a central problem in personalized medicine. Choosing informative data sources and methods that can efficiently incorporate multiple sources is a challenging part of successful analysis in personalized medicine.

BRIEFINGS IN BIOINFORMATICS (2021)

Review Biotechnology & Applied Microbiology

RAS-targeted therapies: is the undruggable drugged?

Amanda R. Moore et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Genetics & Heredity

Predicting drug response of tumors from integrated genomic profiles by deep neural networks

Yu-Chiao Chiu et al.

BMC MEDICAL GENOMICS (2019)

Review Medical Laboratory Technology

The double edge sword of fibrosis in cancer

Chelsea Chandler et al.

TRANSLATIONAL RESEARCH (2019)

Article Oncology

RNA Sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB

William C. Reinhold et al.

CANCER RESEARCH (2019)

Article Multidisciplinary Sciences

Next-generation characterization of the Cancer Cell Line Encyclopedia

Mahmoud Ghandi et al.

NATURE (2019)

Review Oncology

TRPM4 channel and cancer

Yahui Gao et al.

CANCER LETTERS (2019)

Article Medicine, General & Internal

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma

C. Robert et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Medicine, Research & Experimental

Anticancer Drug Response Prediction in Cell Lines Using Weighted Graph Regularized Matrix Factorization

Na-Na Guan et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2019)

Article Biochemical Research Methods

Predicting Cancer Drug Response using a Recommender System

Chayaporn Suphavilai et al.

BIOINFORMATICS (2018)

Review Oncology

Revisiting the role of ABC transporters in multidrug-resistant cancer

Robert W. Robey et al.

NATURE REVIEWS CANCER (2018)

Article Medicine, Research & Experimental

Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer

Alberto Ballestrero et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2017)

Article Biotechnology & Applied Microbiology

A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data

Yuanyuan Li et al.

BMC GENOMICS (2017)

Article Biochemistry & Molecular Biology

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

Matthew G. Rees et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio et al.

Article Genetics & Heredity

Development and verification of the PAM50-based Prosigna breast cancer gene signature assay

Brett Wallden et al.

BMC MEDICAL GENOMICS (2015)

Article Medicine, General & Internal

Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib

Caroline Robert et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Oncology

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

Brinton Seashore-Ludlow et al.

CANCER DISCOVERY (2015)

Review Oncology

The developing story of Sprouty and cancer

Samar Masoumi-Moghaddam et al.

CANCER AND METASTASIS REVIEWS (2014)

Article Oncology

Bleomycin electrochemotherapy in elderly metastatic breast cancer patients: clinical outcome and management considerations

Luca G. Campana et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2014)

Article Biochemistry & Molecular Biology

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Wanjuan Yang et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer

Alvaro Aytes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Pharmacology & Pharmacy

Adenosine Kinase: Exploitation for Therapeutic Gain

Detlev Boison

PHARMACOLOGICAL REVIEWS (2013)

Article Oncology

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

Kevin G. Chen et al.

CLINICAL CANCER RESEARCH (2012)

Article Oncology

BRAF Inhibitors for the Treatment of Metastatic Melanoma: Clinical Trials and Mechanisms of Resistance

Alexander Marzuka Alcala et al.

CLINICAL CANCER RESEARCH (2012)

Article Multidisciplinary Sciences

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett et al.

NATURE (2012)

Article Biotechnology & Applied Microbiology

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)

Laura M. Hodges et al.

PHARMACOGENETICS AND GENOMICS (2011)

Review Peripheral Vascular Disease

Angiotensin inhibition and malignancies: a review

T. Rosenthal et al.

JOURNAL OF HUMAN HYPERTENSION (2009)

Review Medicine, General & Internal

MOLECULAR ORIGINS OF CANCER Gene-Expression Signatures in Breast Cancer

Christos Sotiriou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Biochemistry & Molecular Biology

MAP kinase signalling pathways in cancer

A. S. Dhillon et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Neoplastic transformation and tumorigenesis associated with overexpression of imup-1 and imup-2 genes in cultured NIH/3T3 mouse fibroblasts

Zae Young Ryoo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Multidisciplinary Sciences

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

LT Vassilev et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

Mammalian Sprouty proteins inhibit cell growth and differentiation by preventing Ras activation

I Gross et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Bleomycin upregulates gene expression of angiotensin-converting enzyme via mitogen-activated protein kinase and early growth response 1 transcription factor

RM Day et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)

Article Automation & Control Systems

Monte Carlo cross validation

QS Xu et al.

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS (2001)