4.7 Review

Robotics for enzyme technology: innovations and technological perspectives

Journal

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 105, Issue 10, Pages 4089-4097

Publisher

SPRINGER
DOI: 10.1007/s00253-021-11302-1

Keywords

High-throughput technology; Enzyme technology; Drug delivery; Nanobot; Biofuel

Funding

  1. Department of Science and Technology, New Delhi, Govt. of India, through FIST grant [1196 SR/FST/LS-I/2017/4]
  2. Department of Biotechnology, Government of India [BT/PR27437/BCE/8/1433/2018]
  3. CSIR, India [09/382(0211)/2019-EMR-I]

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The use of robotics in the life science sector has greatly impacted research areas such as enzyme technology, particularly in the field of biomedical applications. Nanobots are increasingly being recognized as essential tools for drug delivery systems, while high-throughput robotic platforms play a crucial role in monitoring and controlling microbial growth conditions during enzyme screening applications.
The use of robotics in the life science sector has created a considerable and significant impact on a wide range of research areas, including enzyme technology due to their immense applications in enzyme and microbial engineering as an indispensable tool in high-throughput screening applications. Scientists are experiencing the advanced applications of various biological robots (nanobots), fabricated based on bottom-up or top-down approaches for making nanotechnology scaffolds. Nanobots and enzyme-powered nanomotors are particularly attractive because they are self-propelled vehicles, which consume biocompatible fuels. These smart nanostructures are widely used as drug delivery systems for the efficient treatment of various diseases. This review gives insights into the escalating necessity of robotics and nanobots and their ever-widening applications in enzyme technology, including biofuel production and biomedical applications. It also offers brief insights into high-throughput robotic platforms that are currently being used in enzyme screening applications for monitoring and control of microbial growth conditions.

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