4.4 Article

Hopf bifurcation of a diffusive SIS epidemic system with delay in heterogeneous environment

Journal

APPLICABLE ANALYSIS
Volume 101, Issue 16, Pages 5906-5931

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/00036811.2021.1909724

Keywords

SIS epidemic system; reaction-diffusion; delay; Hopf bifurcation; stability; Lyapunov-Schmidt reduction; heterogeneous environment; endemic equilibria

Funding

  1. National Natural Science Foundation of China [12071446, 11801089, 11671123]
  2. Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan)

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This paper provides an in-depth qualitative analysis of the dynamic behavior of a diffusive SIS epidemic system with delay in a heterogeneous environment under homogeneous Neumann boundary condition. It explores the stability and effects of nonhomogeneous coefficients on disease-free equilibrium, as well as the existence, multiplicity, and structure of endemic equilibrium. The paper also analyzes the stability of endemic equilibrium, the existence of Hopf bifurcations, and the direction and stability of bifurcating periodic solutions.
This paper performs an in-depth qualitative analysis of the dynamic behavior of a diffusive SIS epidemic system with delay in heterogeneous environment subject to homogeneous Neumann boundary condition. Firstly, we explore the principal eigenvalue to obtain the stability of the disease-free equilibrium (DFE) and the effect of the nonhomogeneous coefficients on the stable region of the DFE. Secondly, we obtain the existence, multiplicity and explicit structure of the endemic equilibrium (EE), i.e., spatially nonhomogeneous steady-state solutions, by using the implicit function theorem and Lyapunov-Schmidt reduction method. Furthermore, by analyzing the distribution of eigenvalues of infinitesimal generators, the stability of EE and the existence of Hopf bifurcations at EE are given. Finally, the direction of Hopf bifurcation and stability of the bifurcating periodic solution are obtained by virtue of normal form theory and center manifold reduction.

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