4.3 Review

Quantum Dots as Biosensors in the Determination of Biochemical Parameters in Xenobiotic Exposure and Toxins

Journal

ANALYTICAL SCIENCES
Volume 37, Issue 5, Pages 661-671

Publisher

SPRINGERNATURE
DOI: 10.2116/analsci.20SCR03

Keywords

Quantum dots; biosensor; toxin; clinical toxicology; biochemical parameters

Funding

  1. Directorate of Forensic Sciences, Tamilnadu State Government

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Quantum dots have been utilized as nanosensors for detecting various toxins in biospecimens, including phytotoxins, vertebrate and invertebrate toxins, and microbial toxins. Additionally, they play a role in indirectly measuring biochemical parameters for poison detection in patient/victim samples.
Quantum dots (QDs) have been exploited for a range of scientific applications where the analytes can be expected to have significant photoluminescent properties. Previously, the applications of QDs as nanosensors for the detection of toxics in biospecimens, especially in cases of poisoning, have been discussed. This review focuses on the applications of QDs as biosensors for the detection of phytotoxins, vertebrate and invertebrate toxins, and microbial toxins present in biospecimens. Further, the role of QDs in the measurement of biochemical parameters of patient/victim as an indirect method of poison detection is also highlighted.

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