Impact of an automated multiple emitter whole-room ultraviolet-C disinfection system on hospital acquired infections: A quasi-experimental study

A quasi-experimental study performed in a pediatric hematology-oncology unit demonstrated that whole-room ultraviolet-C disinfection was associated with a significant reduction in hospital-onset Clostridioides dif-ficile infection (P< .01, trend and level), but not healthcare-associated viral respiratory infections (P= .06 for trend, P= .36 for level) or central line-associated bloodstream infections (P> 0.75, trend and level). (c) 2021 Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.

Automated summary

A quasi-experimental study conducted in a pediatric hematology-oncology unit showed that whole-room ultraviolet-C disinfection significantly reduced hospital-onset Clostridioides difficile infection, but did not affect healthcare-associated viral respiratory infections or central line-associated bloodstream infections.