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Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan
Fumiaki Obata et al.
NATURE COMMUNICATIONS (2015)
Drosophila nervous system as a target of aging and anti-aging interventions
Leonid V. Omelyanchuk et al.
FRONTIERS IN GENETICS (2015)
Hypoxia disrupts proteostasis in Caenorhabditis elegans
Emily M. Fawcett et al.
AGING CELL (2015)
mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3
K. M. Dodd et al.
ONCOGENE (2015)
CD47 signaling pathways controlling cellular differentiation and responses to stress
David R. Soto-Pantoja et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)
ATF4 activity: a common feature shared by many kinds of slow-aging mice
Weiquan Li et al.
AGING CELL (2014)
Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
Duc Tran et al.
AGING CELL (2014)
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
Michael B. Stout et al.
AGING-US (2014)
Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate
Halina Jurkowska et al.
AMINO ACIDS (2014)
Sulfur as a Signaling Nutrient Through Hydrogen Sulfide
Omer Kabil et al.
ANNUAL REVIEW OF NUTRITION, VOL 34 (2014)
Sulfhydration of p66Shc at Cysteine59 Mediates the Antioxidant Effect of Hydrogen Sulfide
Zhi-Zhong Xie et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans
Bedoor Qabazard et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Enzymology of H2S Biogenesis, Decay and Signaling
Omer Kabil et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Lithium salts - Simple but magic
E. Y. Plotnikov et al.
BIOCHEMISTRY-MOSCOW (2014)
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms
Csaba Szabo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
The vertebrate homologue of sulfide-quinone reductase in mammalian mitochondria
M. Ackermann et al.
CELL AND TISSUE RESEARCH (2014)
Endothelial Dysfunction: The Link Between Homocysteine and Hydrogen Sulfide
Sathnur Pushpakumar et al.
CURRENT MEDICINAL CHEMISTRY (2014)
S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair
Kexin Zhao et al.
EMBO REPORTS (2014)
Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders
Alisia Carnemolla et al.
HUMAN MOLECULAR GENETICS (2014)
Decreased Cystathionine-γ- lyase ( CSE) Activity in Livers of Type 1 Diabetic Rats and Peripheral Blood Mononuclear Cells ( PBMC) of Type 1 Diabetic Patients
Prasenjit Manna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway
Marouane Libiad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and Longevity
Elissa S. Epel et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells
Meihua Zheng et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)
Hydrogen sulfide reduces regional myocardial ischemia injury through protection of mitochondrial function
Ying-Hua Xie et al.
MOLECULAR MEDICINE REPORTS (2014)
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Randall M. Chin et al.
NATURE (2014)
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
Bindu D. Paul et al.
NATURE (2014)
H2S during circulatory shock: Some unresolved questions
Oscar McCook et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2014)
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro
Bartosz Szczesny et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2014)
Hydrogen sulfide promotes proliferation and neuronal differentiation of neural stem cells and protects hypoxia-induced decrease in hippocampal neurogenesis
Dexiang Liu et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Gasotransmitters: growing pains and joys
Rui Wang
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Regulated spatial organization and sensitivity of cytosolic protein oxidation in Caenorhabditis elegans
Catalina Romero-Aristizabal et al.
NATURE COMMUNICATIONS (2014)
Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification
Christoph Ruckenstuhl et al.
PLOS GENETICS (2014)
Involvement of trehalose in hydrogen sulfide donor sodium hydrosulfide-induced the acquisition of heat tolerance in maize (Zea mays L.) seedlings
Zhong-Guang Li et al.
BOTANICAL STUDIES (2014)
Hydrogen sulfide as a potential biomarker of asthma
Kian F. Chung
EXPERT REVIEW OF RESPIRATORY MEDICINE (2014)
Thiosulfate: a readily accessible source of hydrogen sulfide in oxygen sensing
Kenneth R. Olson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
Hydrogen Sulfide Treatment Promotes Glucose Uptake by Increasing Insulin Receptor Sensitivity and Ameliorates Kidney Lesions in Type 2 Diabetes
Rong Xue et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2
Guangdong Yang et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?
David Gems et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H2S/HS- Production and Evidence of Pancreatic and Lung Toxicity
Heather B. Roman et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Polysulfides Link H2S to Protein Thiol Oxidation
Romy Greiner et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Nuclear glutathione
Jose Luis Garcia-Gimenez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Brg1-dependent epigenetic control of vascular smooth muscle cell proliferation by hydrogen sulfide
Li Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
Ana P. Gomes et al.
CELL (2013)
Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
Filipe Cabreiro et al.
CELL (2013)
Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis
Sarathi Mani et al.
CIRCULATION (2013)
Hydrogen Sulfide Impairs Glucose Utilization and Increases Gluconeogenesis in Hepatocytes
Ling Zhang et al.
ENDOCRINOLOGY (2013)
Biphasic dose responses in biology, toxicology and medicine: Accounting for their generalizability and quantitative features
Edward J. Calabrese
ENVIRONMENTAL POLLUTION (2013)
Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics
Katalin Modis et al.
FASEB JOURNAL (2013)
Polysulfide exerts a protective effect against cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells
Shin Koike et al.
FEBS LETTERS (2013)
Hydrogen sulphide suppresses human atrial fibroblast proliferation and transformation to myofibroblasts
Jingwei Sheng et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2013)
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
Tamara Tchkonia et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Mice Deficient in Cystathionine Beta Synthase Display Increased Dyrk1A and SAHH Activities in Brain
Chris Planque et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2013)
Mitonuclear protein imbalance as a conserved longevity mechanism
Riekelt H. Houtkooper et al.
NATURE (2013)
Sulfur-based redox alterations in long-lived Snell dwarf mice
Victor Vitvitsky et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2013)
Hydrogen sulfide chemical biology: Pathophysiological roles and detection
Gopi K. Kolluru et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2013)
C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2
Bedoor Qabazard et al.
PLOS ONE (2013)
Pheromone sensing regulates Caenorhabditis elegans lifespan and stress resistance via the deacetylase SIR-2.1
Andreas H. Ludewig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
L-Cysteine Efflux in Erythrocytes As A Function of Human Age: Correlation with Reduced Glutathione and Total Anti-Oxidant Potential
Prabhanshu Kumar et al.
REJUVENATION RESEARCH (2013)
Short chain fatty acids and their receptors: new metabolic targets
Brian T. Layden et al.
TRANSLATIONAL RESEARCH (2013)
A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells
Norihiro Shibuya et al.
NATURE COMMUNICATIONS (2013)
Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria
Noriyuki Nagahara et al.
SCIENTIFIC REPORTS (2013)
Are other fluorescent tags used instead of ethidium bromide safer?
Soodabeh Saeidnia et al.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Hydrogen sulfide in cell signaling, signal transduction, cellular bioenergetics and physiology in C. elegans
Katalin Modis et al.
GENERAL PHYSIOLOGY AND BIOPHYSICS (2013)
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
Antero Salminen et al.
AGEING RESEARCH REVIEWS (2012)
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
Diana Jurk et al.
AGING CELL (2012)
Cystathionine beta synthase modulates senescence of human endothelial cells
Eva Albertini et al.
AGING-US (2012)
High Turnover Rates for Hydrogen Sulfide Allow for Rapid Regulation of Its Tissue Concentrations
Victor Vitvitsky et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS
D. R. Linden et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO
Stacey Robida-Stubbs et al.
CELL METABOLISM (2012)
Does the oxidative stress theory of aging explain longevity differences in birds? II. Antioxidant systems and oxidative damage
Magdalene K. Montgomery et al.
EXPERIMENTAL GERONTOLOGY (2012)
Effect of H2S on the circadian rhythm of mouse hepatocytes
Zhanxian Shang et al.
LIPIDS IN HEALTH AND DISEASE (2012)
PHYSIOLOGICAL IMPLICATIONS OF HYDROGEN SULFIDE: A WHIFF EXPLORATION THAT BLOSSOMED
Rui Wang
PHYSIOLOGICAL REVIEWS (2012)
Formation and Regulation of Adaptive Response in Nematode Caenorhabditis elegans
Y. -L. Zhao et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Hydrogen Sulfide as an Endogenous Modulator in Mitochondria and Mitochondria Dysfunction
Wei Guo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation
Aswin Mangerich et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Solubility and Permeation of Hydrogen Sulfide in Lipid Membranes
Ernesto Cuevasanta et al.
PLOS ONE (2012)
Astrocyte Senescence as a Component of Alzheimer's Disease
Rekha Bhat et al.
PLOS ONE (2012)
HIF-1 modulates longevity and healthspan in a temperature-dependent manner
Scott F. Leiser et al.
AGING CELL (2011)
Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide
Iori Ueki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
The therapeutic potential of hydrogen sulfide: separating hype from hope
Kenneth R. Olson
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
Free and Acid-Labile Hydrogen Sulfide Concentrations in Mouse Tissues: Anomalously High Free Hydrogen Sulfide in Aortic Tissue
Michael D. Levitt et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide
Yuko Kurokawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide
Yoshinori Mikami et al.
BIOCHEMICAL JOURNAL (2011)
PLP-dependent H2S biogenesis
Sangita Singh et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2011)
Increase of Drosophila melanogaster lifespan due to D-GADD45 overexpression in the nervous system
E. N. Plyusnina et al.
BIOGERONTOLOGY (2011)
Respiratory chain cysteine and methionine usage indicate a causal role for thiyl radicals in aging
Bernd Moosmann
EXPERIMENTAL GERONTOLOGY (2011)
The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation
Anna A. Powolny et al.
EXPERIMENTAL GERONTOLOGY (2011)
A critical life-supporting role for cystathionine γ-lyase in the absence of dietary cysteine supply
Sarathi Mani et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
The Response of Caenorhabditis elegans to Hydrogen Sulfide and Hydrogen Cyanide
Mark W. Budde et al.
GENETICS (2011)
Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur
Martha H. Stipanuk et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2011)
Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
Silvestre Alavez et al.
NATURE (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
THE VERTEBRATE HOMOLOG OF SULFIDE-QUINONE REDUCTASE IS EXPRESSED IN MITOCHONDRIA OF NEURONAL TISSUES
M. Ackermann et al.
NEUROSCIENCE (2011)
HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans
Dana L. Miller et al.
PLOS ONE (2011)
Correction: The Long Life of Birds: The Rat-Pigeon Comparison Revisited
Magdalene K. Montgomery et al.
PLoS One (2011)
Hydrogen Sulfide Attenuates Carbon Tetrachloride-Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats
Gang Tan et al.
PLOS ONE (2011)
Increased transsulfuration mediates longevity and dietary restriction in Drosophila
Hadise Kabil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
H2S: A Universal Defense Against Antibiotics in Bacteria
Konstantin Shatalin et al.
SCIENCE (2011)
mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
Vanessa S. Rodrik-Outmezguine et al.
CANCER DISCOVERY (2011)
Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans
Felipe Surco-Laos et al.
FOOD & FUNCTION (2011)
The hydrogen sulfide signaling system: changes during aging and the benefits of caloric restriction
Benjamin L. Predmore et al.
AGE (2010)
Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models
Li-Fang Hu et al.
AGING CELL (2010)
Trehalose extends longevity in the nematode Caenorhabditis elegans
Yoko Honda et al.
AGING CELL (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Endogenous Production of H2S in the Gastrointestinal Tract: Still in Search of a Physiologic Function
David R. Linden et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Low Levels of Hydrogen Sulfide in the Blood of Diabetes Patients and Streptozotocin-Treated Rats Causes Vascular Inflammation?
Sushil K. Jain et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Hydrogen Sulfide: From Brain to Gut
Hideo Kimura
ANTIOXIDANTS & REDOX SIGNALING (2010)
Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster
Agnesa Avanesian et al.
BIOGERONTOLOGY (2010)
The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging
Scott F. Leiser et al.
BIOLOGICAL CHEMISTRY (2010)
Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide
Christopher F. Toombs et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells
Guangdong Yang et al.
CARDIOVASCULAR RESEARCH (2010)
Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract
Gary R. Martin et al.
DIGESTIVE AND LIVER DISEASE (2010)
The Differential Modulation on Cytochrome P450 Enzymes by Garlic Components
Tao Zeng et al.
FOOD REVIEWS INTERNATIONAL (2010)
The Dual Role of Senescence in Tumorigenesis
Lilian Chuaire-Noack et al.
INTERNATIONAL JOURNAL OF MORPHOLOGY (2010)
Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury
Isao Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Hydrogen sulfide exposure increases desiccation tolerance in Drosophila melanogaster
Jian-Feng Zhong et al.
JOURNAL OF INSECT PHYSIOLOGY (2010)
Hydrogen sulphide induces μ opioid receptor-dependent analgesia in a rodent model of visceral pain
Eleonora Distrutti et al.
MOLECULAR PAIN (2010)
Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy
Carlo Viscomi et al.
NATURE MEDICINE (2010)
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
Aswin Mangerich et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2010)
Satellite cell characterization from aging human muscle
Arianna Corbu et al.
NEUROLOGICAL RESEARCH (2010)
A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans
Wen Yang et al.
PLOS BIOLOGY (2010)
Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition
Ritsuko Nakano-Kurimoto et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels
M. H. Stipanuk et al.
AMINO ACIDS (2009)
3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain
Norihiro Shibuya et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
A Source of Hydrogen Sulfide and a Mechanism of Its Release in the Brain
Mari Ishigami et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Physiological and pharmacological features of the novel gasotransmitter: Hydrogen sulfide
Daniele Mancardi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification
Dominick G. A. Burton et al.
EXPERIMENTAL GERONTOLOGY (2009)
Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia
Sapna Gupta et al.
FASEB JOURNAL (2009)
Glucose-induced production of hydrogen sulfide may protect the pancreatic beta-cells from apoptotic cell death by high glucose
Yukiko Kaneko et al.
FEBS LETTERS (2009)
H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia
Taurai Chiku et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions
Sangita Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age
Liou Sun et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats
Lingyun Wu et al.
LABORATORY INVESTIGATION (2009)
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Matilde Murga et al.
NATURE GENETICS (2009)
Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy
Valeria Tiranti et al.
NATURE MEDICINE (2009)
A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan
Ayumi Shibamura et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
Anat Ben-Zvi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
No facilitator required for membrane transport of hydrogen sulfide
John C. Mathai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Comparison of the metabolic and ventilatory response to hypoxia and H2S in unsedated mice and rats
Philippe Haouzi et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2009)
Remarkable longevity and stress resistance of nematode PI3K-null mutants
Srinivas Ayyadevara et al.
AGING CELL (2008)
Radical-free biology of oxidative stress
Dean P. Jones
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values
Julie Furne et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Hydrogen sulfide raises cytosolic calcium in neurons through activation of L-type Ca2+ channels
Miguel Angel Garcia-Bereguiain et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
Thomas Kuilman et al.
CELL (2008)
Characterization of a novel, water-soluble hydrogen sulfide - Releasing molecule (GYY4137): New insights into the biology of hydrogen sulfide
Ling Li et al.
CIRCULATION (2008)
Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria
Tatjana M. Hildebrandt et al.
FEBS JOURNAL (2008)
Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake
Ming Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
Camilla A. Hansson Petersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
L-cysteine influx in erythrocytes as a function of human age
Syed Ibrahim Rizvi et al.
REJUVENATION RESEARCH (2008)
H2S as a physiologic vasorelaxant:: Hypertension in mice with deletion of cystathionine γ-lyase
Guangdong Yang et al.
SCIENCE (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans
Dana L. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The novel gaseous vasorelaxant hydrogen sulfide inhibits angiotensin-converting enzyme activity of endothelial cells
Hilde Laggner et al.
JOURNAL OF HYPERTENSION (2007)
Cellular senescence and chromatin structure
Ryo Funayama et al.
CHROMOSOMA (2007)
Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons
Nam Sang Cheung et al.
NEUROPHARMACOLOGY (2007)
Longevity determined by developmental arrest genes in Caenorhabditis elegans
Di Chen et al.
AGING CELL (2007)
Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-κB pathway
Liang Zhi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Astrocytes aged in vitro show a decreased neuroprotective capacity
M. Pertusa et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Hydrogen sulfide induces direct radical-associated DNA damage
Matias S. Attene-Ramos et al.
MOLECULAR CANCER RESEARCH (2007)
Hydrogen sulfide acts as a mediator of inflammation inacute pancreatitis:: in vitro studies using isolated mouse pancreatic acinar cells
Ramasamy Tamizhselvi et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2007)
Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells
Rajamanickam Baskar et al.
FASEB JOURNAL (2007)
Pathomolecular effects of homocysteine on the aging process: A new theory of aging
Felipe P. Perez et al.
MEDICAL HYPOTHESES (2007)
H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells
Guangdong Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Thioredoxin-2 affects lifespan and oxidative stress in Drosophila
Malin J. Svensson et al.
HEREDITAS (2007)
Life-long vitamin C supplementation in combination with cold exposure does not affect oxidative damage or lifespan in mice, but decreases expression of antioxidant protection genes
Colin Selman et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2006)
High oxidative damage levels in the longest-living rodent, the naked mole-rat
Blazej Andziak et al.
AGING CELL (2006)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Aging and immortality - Quasi-programmed senescence and its pharmacologic inhibition
Mikhail V. Blagosklonny
CELL CYCLE (2006)
Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide
Yang Cao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Evidence for a functional genetic polymorphism of the human thiosulfate sulfurtransferase (Rhodanese), a cyanide and H2S detoxification enzyme
Ingrid Billaut-Laden et al.
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