4.7 Article

Ionic liquid mediated green synthesis of Ag-Au/Y2O3 nanoparticles using leaves extracts of Justicia adhatoda: Structural characterization and its biological applications

Journal

ADVANCED POWDER TECHNOLOGY
Volume 32, Issue 7, Pages 2213-2225

Publisher

ELSEVIER
DOI: 10.1016/j.apt.2021.04.030

Keywords

Justicia adhatoda; [BMIM] PF6; Ag-Au/Y2O3; S. aureus; E. coli; Cervical cancer

Funding

  1. RUSAPhase 2.0 [Policy (TNMulti -Gen) , Dept. of. Edn. Govt. of India] [F.2451/2014 -U]
  2. [Ph.D/1564/AURF Fellowship/2017]

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A facile synthesis was used to prepare silver-gold decorated yttrium oxide nanoparticles using Justicia adhatoda (leaves extract) and [BMIM] PF6 (Ionic liquid) as capping/stabilizing agent. The nanoparticles exhibited a face-center cubic structure, good antibacterial and anticancer activities.
In the present work, a facile synthesis was applied for the silver-gold decorated yttrium oxide nanoparticles with the use of Justicia adhatoda (leaves extract) and [BMIM] PF6 (Ionic liquid) as a capping/stabilizing agent. The XRD analysis showed that Ag-Au/Y2O3 nanoparticles have a face-center cubic structure and crystallite size of 30 nm. The Y-O stretching bands were observed in the FT-IR spectrum at 464 to 495 cm-1. The band gap of the silver-gold decorated Y2O3 nanoparticles was estimated as 5.75 eV from the UV-DRS spectrum. In the SEM and TEM images, the morphology of silver-gold/Y2O3 nanoparticles shows a nanoflake-like structure. The presence of silver, gold, yttrium and oxygen of elements has been confirmed by the EDX spectrum. The antibacterial activity of the nanoparticles was evaluated for the Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative) bacteria. The anticancer activity was also studied by the human cervical cancer cell line. The silver-gold decorated yttrium oxide nanoparticles revealed an exceptional microbicidal and antitumor activity when compared with yttrium oxide, silver decorated yttrium oxide and gold decorated yttrium oxide. (C) 2021 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.

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