High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: A multinational experience in 990 cases from Latin America

Article Infectious Diseases

Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study

Carolina Garcia-Vidal et al.

Summary: The study found that co-infections and superinfections in hospitalized COVID-19 patients were relatively low compared to other viral pandemics. Patients experienced worse outcomes after hospital-acquired superinfections occurred.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Letter Public, Environmental & Occupational Health

Pediatric antimicrobial stewardship in the COVID-19 outbreak

Eneritz Velasco-Arnaiz et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2021)

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Article Public, Environmental & Occupational Health

Impact of COVID-19 prevention measures on risk of health care-associated Clostridium difficile infection

Enrico Bentivegna et al.

Summary: The study found a significant decrease in healthcare-associated C. difficile infection incidence during the COVID-19 pandemic, suggesting that measures to prevent microorganism transmission can effectively reduce such infections and related costs.

AMERICAN JOURNAL OF INFECTION CONTROL (2021)

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Editorial Material Infectious Diseases

Understanding the role of bacterial and fungal infection in COVID-19

Timothy M. Rawson et al.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Article Immunology

COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children A Multinational Study

Omar Yassef Antunez-Montes et al.

Summary: This study found a more severe form of COVID-19 and a high number of MIS-C cases in Latin American children compared to studies from China, Europe, and North America, indicating a more severe disease in Latin/Hispanic children or those of lower socioeconomic status. There is an urgent need for more data on COVID-19 in Latin America.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2021)

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Review Pediatrics

Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults A Systematic Review and Meta-analysis

Russell M. Viner et al.

Summary: This systematic review and meta-analysis found that children and adolescents have a 44% lower odds of secondary infection with SARS-CoV-2 compared to adults, with insufficient data to determine if children transmit the virus less than adults. Preliminary evidence suggests that children have a lower susceptibility to SARS-CoV-2 infection compared with adults, but their role in virus transmission remains unclear.

JAMA PEDIATRICS (2021)

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Review Pediatrics

A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process

Rachel Harwood et al.

Summary: PIMS-TS is a newly discovered condition associated with COVID-19, and a national consensus management pathway has been developed for UK clinicians caring for affected children. The guidance emphasizes the importance of a multidisciplinary team in decision-making and recommends treatment options including supportive care, immunoglobulin, steroids, and biological therapies. This guidance provides a solid framework for clinicians caring for children with PIMS-TS in the UK and will be updated based on future evidence.

LANCET CHILD & ADOLESCENT HEALTH (2021)

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Article Pediatrics

Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States

L. Charles Bailey et al.

Summary: This cohort study of US pediatric patients found low rates of SARS-CoV-2 infection, with mild clinical manifestations. Infection was associated with Black, Hispanic, and Asian race/ethnicity, adolescence and young adulthood, as well as non-respiratory chronic medical conditions. The study suggests higher concern may be warranted for patients with complex medical conditions or minority race/ethnicity.

JAMA PEDIATRICS (2021)

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Editorial Material Infectious Diseases