Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 13, Issue 20, Pages 24228-24237Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.1c02673
Keywords
chiral separation; ionic liquid; enantioselective seperation; porous carbon; chiral carbon; chiral composite
Funding
- German-Israeli Foundation for Scientific Research and Development (GIF) [I-87-302.10-2015]
Ask authors/readers for more resources
This study discusses the importance of using porous materials for chiral separation and synthesis, with a focus on the application of carbon materials in these processes. A new method for preparing chiral carbon composite materials is proposed, which can be used for chiral recognition of molecules.
Chiral separation and asymmetric synthesis and catalysis are crucial processes for obtaining enantiopure compounds, which are especially important in the pharmaceutical industry. The efficiency of the separation processes is readily increased by using porous materials as the active material can interact with a larger surface area. Silica, metal-organic frameworks, or chiral polymers are versatile porous materials that are established in chiral applications, but their instability under certain conditions in some cases requires the use of more stable porous materials such as carbons. In addition to their stability, porous carbon materials can be tailored for their ability to adsorb and catalytically activate different chemical compounds from the liquid and the gas phase. The difficulties imposed by the functionalization of carbons with chiral species were tackled in the past by carbonizing chiral ionic liquids (CILs) together with a template to create pores, which results in the entire body of a material that is built up from the precursor. To increase the atomic efficiency of ionic liquids for better economic utilization of CILs, the approach presented here is based on the formation of a composite between CIL-derived chiral carbon and a pristine carbon material obtained from carbohydrate precursors. Two novel enantioselective carbon composite materials are applied for the chiral recognition of molecules in the gas phase, as well as in solution. The enantiomeric ratio of the L-composite for phenylalanine from the solution was (L/D) = 8.4, and for 2-butanol from the gas phase, it was (S/R) = 1.3. The D-composite showed an opposite behavior, where the enantiomeric ratio for phenylalanine was (D/L) = 2.7, and for 2-butanol from the gas phase, it was (R/S) = 1.3.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available