Journal
GLOBAL SPINE JOURNAL
Volume 12, Issue 8, Pages 1804-1813Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/2192568221989291
Keywords
thoracolumbar kyphosis (TLK); achondroplasia (ACH); posterior vertebral column resection (pVCR); complications
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This retrospective study evaluated the safety and effectiveness of posterior vertebral column resection for severe thoracolumbar kyphosis in achondroplasia patients. The surgery showed good correction of TLK and improved neurological function, but had relatively high surgical complication rates.
Study Design: Retrospective cohort study. Objective: We aimed to evaluate the safety and validity of posterior vertebral column resection (pVCR) for severe thoracolumbar kyphosis (TLK) in the achondroplasia (ACH) patients. Methods: Seven ACH patients (male: female = 6:1) who underwent pVCR procedures due to severe TLK from December 2008 to December 2017 in the authors' hospital were included in this retrospective study. Their mean follow-up duration was 67 +/- 35 months. Their clinical characteristics, radiologic characteristics, surgical characteristics and surgical complications were reviewed. Results: A total of 8 vertebrae were removed with an average of 5 +/- 2 levels of decompression and 9 +/- 2 segments instrumented. The mean correction rates of TLKs and the main curves were 73 +/- 15% and 87 +/- 6%, respectively. Five patients (71%) had preoperative neurological symptoms with a mean Japanese Orthopedic Association (JOA) score of 8 +/- 3 points. Their neurological functions were all improved, with a recovery rate of 78 +/- 32% for the JOA score at the last follow-up. Four patients (57%) suffered from surgical complications, including rod breakages (43%), neurological complications (28%), dural tears (14%), cerebrospinal fluid leaks (14%) and proximal junction kyphosis (14%). Conclusions: pVCR can offer a good correction for TLK and improve neurological function with extensive laminectomies in ACH patients. But the morbidity of surgical complications is relatively high. Therefore, it is a reserved surgical option for severe TLK in ACH patients by experienced spinal surgeons, especially with apical markedly hypoplastic vertebrae.
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