4.6 Review

Type 2 Diabetes and Myocardial Infarction: Recent Clinical Evidence and Perspective

Journal

FRONTIERS IN CARDIOVASCULAR MEDICINE
Volume 8, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fcvm.2021.644189

Keywords

type 2 diabetes; myocardial infarction; evidence-based medicine; drug; sodium-glucose cotransporter-2 inhibitor

Funding

  1. Outstanding Youth Foundation of National Natural Science Foundation [82022076]
  2. Special Project for Outstanding Young Talents of China Academy of Chinese Medical Sciences [ZZ13-YQ-001, ZZ13-YQ-001-A1]

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T2DM and its complications, particularly myocardial infarction (MI), pose significant health risks globally. It is crucial to actively treat CAD in T2DM patients to reduce the risk of MI recurrence. The latest clinical evidence-based research emphasizes the relationship between T2DM and MI, highlighting the need for further investigation in this field.
Type 2 diabetes mellitus (T2DM) and its complications are seriously affecting public health worldwide. Myocardial infarction (MI) is the primary cause of death in patients with T2DM. T2DM patients without a history of coronary artery disease (CAD) have the same risk of major coronary events as those with CAD; T2DM patients with a history of MI have >40% risk of recurrence of MI. Thus, CAD in patients with T2DM needs to be treated actively to reduce the risk of MI. The cardiology community focused on the role of T2DM in the development of CAD and on the related issues of T2DM and MI with respect to comorbidities, prognosis, drug therapy, and heredity. In this mini review, the latest progress of clinical evidence-based research between T2DM and MI in recent years was reviewed, and the possible research directions in this field were considered and prospected.

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