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Preeclampsia: Pathophysiology and management

Publisher

ELSEVIER MASSON, CORP OFF
DOI: 10.1016/j.jogoh.2020.101975

Keywords

Preeclampsia; Hypertension; Pregnancy complication; Placenta; Angiogenic-antiangiogenic factors

Funding

  1. Department of Biotechnology (DBT), Govt. of India
  2. Science and Engineering and Research Board (SERB), Department of Science and Technology, New Delhi, India

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Preeclampsia is a pregnancy-related disorder characterized by hypertension, with placental and maternal types. The incidence is about 8-10%, and despite improved understanding of the condition in recent years, clinical testing remains challenging.
Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset of hypertension during pregnancy. The preeclampsia can be of two types, placental or maternal preeclampsia. Among these two types former, i.e., placental preeclampsia is more severe than the latter. According to the recent survey by National Health Portal of India, the incidence of preeclampsia is about 8-10 % among pregnant women. Though our understanding of preeclampsia has improved in recent years, the development and interpretation of the clinical tests remain difficult for preeclampsia. Hence, we have made an attempt to understand the pathophysiology, associated conditions/consequences, treatment and management/prevention of the condition in this review. (C) 2020 Published by Elsevier Masson SAS.

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