4.7 Article

The National Children's Study Archive Model: A 3-Tier Framework for Dissemination of Data and Specimens for General Use and Secondary Analysis

Journal

FRONTIERS IN PUBLIC HEALTH
Volume 9, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fpubh.2021.526286

Keywords

biological specimen bank; child health; data archive; data exploration; data sharing; environmental sample bank; information dissemination; longitudinal studies

Funding

  1. National Institutes of Health
  2. NICHD [HHSN275201500050U]

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The National Children's Study Archive (NCSA) was established as a repository for samples, data, and information to provide qualified researchers with access for secondary research. The NCSA model offers a 3-tiered access system designed to allow users to explore and request data and samples at different levels.
The National Children's Study (NCS) Archive was created as a repository of samples, data, and information from the NCS Vanguard Study-a longitudinal pregnancy and birth cohort evaluating approaches to study influence of environmental exposures on child health and development-to provide qualified researchers with access to NCS materials for use in secondary research. The National Children's Study Archive (NCSA) model is a 3-tiered access model designed to make the wealth of information and materials gathered during the NCS Vanguard Study available at a user appropriate level. The NCSA model was developed as a 3-tier framework, for users of varying access levels, providing intuitive data exploration and visualization tools, an end-to-end data and sample request management system, and a restricted portal for participant-level data access with a team of experts available to assist users. This platform provides a model to accelerate transformation of information and materials from existing studies into new scientific discoveries.

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