Omics-Driven Biotechnology for Industrial Applications

Biomanufacturing is a key component of biotechnology that uses biological systems to produce bioproducts of commercial relevance, which are of great interest to the energy, material, pharmaceutical, food, and agriculture industries. Biotechnology-based approaches, such as synthetic biology and metabolic engineering are heavily reliant on omics driven systems biology to characterize and understand metabolic networks. Knowledge gained from systems biology experiments aid the development of synthetic biology tools and the advancement of metabolic engineering studies toward establishing robust industrial biomanufacturing platforms. In this review, we discuss recent advances in omics technologies, compare the pros and cons of the different omics technologies, and discuss the necessary requirements for carrying out multi-omics experiments. We highlight the influence of omics technologies on the production of biofuels and bioproducts by metabolic engineering. Finally, we discuss the application of omics technologies to agricultural and food biotechnology, and review the impact of omics on current COVID-19 research.

Automated summary

Biomanufacturing, a key component of biotechnology, utilizes biological systems to produce commercial bioproducts which are of interest to various industries. Technologies like synthetic biology and metabolic engineering heavily rely on omics driven systems biology for research and development, aiding in the establishment of industrial biomanufacturing platforms. These technologies have a significant impact on the production of biofuels, bioproducts, agricultural and food biotechnology, as well as current COVID-19 research.