Journal
PROCESSES
Volume 9, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/pr9020321
Keywords
clinical trial; hyaluronic acid; Lonicerae flos; moisturizing; microneedle patch
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The study found that utilizing cosmetic raw materials such as hyaluronic acid and Lonicerae flos in a microneedle patch for medicinal purposes can effectively moisturize the skin, potentially benefiting the development of relevant industries.
The utilization of cosmetic raw materials for medicinal purposes in a microneedle patch containing hyaluronic acid (HA) and Lonicerae flos ethanol extract (LEE) has increased based on their eco-friendly characteristics. The moisturizing effects of this microneedle patch were assessed on the forearms of 20 female participants, and our results showed an increase between 29.60% and 88.54% in skin moisture content at the same time points relative to the untreated group. Apart from confirming the safety of HA and Lonicerae flos, our findings may also promote the use of HA and medicinal herbs in relevant industries, indicating their potential as raw ingredients for the development of cosmetic products and topical dermatological drugs. The results suggested that HA, Lonicerae flos, and other combinations of chemical and natural products based on traditional oriental medicine could beneficially affect skin health.
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