4.7 Review

Association of risk factors with type 2 diabetes: A systematic review

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Publisher

ELSEVIER
DOI: 10.1016/j.csbj.2021.03.003

Keywords

Aging; Cardiovascular disease; Depression; Diabetes mellitus; Dyslipidemia; Ethnicity; Family history of diabetes; Hypertension; Physical inactivity; Prevention; Risk factors; Serum uric acid; Sleep quality; Sleep quantity; Smoking; Type 2 diabetes; Obesity

Funding

  1. National Water and Energy Center of the United Arab Emirates University [31R215]

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Diabetes is a leading cause of severe health complications and death globally, with no cure available, requiring preventive measures. This systematic review identifies major risk factors for type 2 diabetes incidence/prevalence and analyzes their impact on the disease. Insights and recommendations are provided for better diagnosis and prognosis, targeting healthcare professionals, individuals, and government institutions.
Diabetes is the leading cause of severe health complications and one of the top 10 causes of death worldwide. To date, diabetes has no cure, and therefore, it is necessary to take precautionary measures to avoid its occurrence. The main aim of this systematic review is to identify the majority of the risk factors for the incidence/prevalence of type 2 diabetes mellitus on one hand, and to give a critical analysis of the cohort/cross-sectional studies which examine the impact of the association of risk factors on diabetes. Consequently, we provide insights on risk factors whose interactions are major players in developing diabetes. We conclude with recommendations to allied health professionals, individuals and government institutions to support better diagnosis and prognosis of the disease. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.

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