Related references
Note: Only part of the references are listed.Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death
Changfeng Li et al.
AUTOPHAGY (2021)
Autophagy as a therapeutic target in pancreatic cancer
Max Piffoux et al.
BRITISH JOURNAL OF CANCER (2021)
CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer
Jin Huang et al.
GUT (2021)
Regulation and function of autophagy in pancreatic cancer
Jingbo Li et al.
AUTOPHAGY (2021)
Ferroptosis is a type of autophagy-dependent cell death
Borong Zhou et al.
SEMINARS IN CANCER BIOLOGY (2020)
TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status
Chen Liang et al.
AUTOPHAGY (2020)
Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome
Sangeetha N. Kalimuthu et al.
GUT (2020)
Alkaliptosis: a new weapon for cancer therapy
Jiao Liu et al.
CANCER GENE THERAPY (2020)
Mitochondria as multifaceted regulators of cell death
Florian J. Bock et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
Enyong Dai et al.
AUTOPHAGY (2020)
Glycolysis promotes the progression of pancreatic cancer and reduces cancer cell sensitivity to gemcitabine
Shangnan Dai et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Oncogenic K-ras Induces Mitochondrial OPA3 Expression to Promote Energy Metabolism in Pancreatic Cancer Cells
Ning Meng et al.
CANCERS (2020)
Cysteine depletion induces pancreatic tumor ferroptosis in mice
Michael A. Badgley et al.
SCIENCE (2020)
ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity
Sonia Alcala et al.
NATURE COMMUNICATIONS (2020)
Mammalian STE20-like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2-mediated mitophagy
Yongli Hu et al.
MOLECULAR MEDICINE REPORTS (2020)
The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside
Kivanc Gorgulu et al.
CELLS (2020)
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Keisuke Yamamoto et al.
NATURE (2020)
Interplay Between Lipid Metabolism and Autophagy
Yangchun Xie et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma
Jae-Seon Lee et al.
CANCERS (2020)
Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway
Enyong Dai et al.
NATURE COMMUNICATIONS (2020)
Mitophagy Receptors in Tumor Biology
Yangchun Xie et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Autophagy-Dependent Ferroptosis: Machinery and Regulation
Jiao Liu et al.
CELL CHEMICAL BIOLOGY (2020)
Increased autophagy/mitophagy levels in primary tumours of patients with pancreatic neuroendocrine neoplasms
Kosmas Daskalakis et al.
ENDOCRINE (2020)
The Role of Autophagy in Pancreatic Cancer-Recent Advances
Maria New et al.
BIOLOGY-BASEL (2020)
Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity
Rui Kang et al.
AUTOPHAGY (2019)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Kirsten L. Bryant et al.
NATURE MEDICINE (2019)
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways
Shengnan Jia et al.
CELL DEATH & DISEASE (2019)
The molecular machinery of regulated cell death
Daolin Tang et al.
CELL RESEARCH (2019)
NIPSNAP1 and NIPSNAP2 Act as Eat Me Signals for Mitophagy
Yakubu Princely Abudu et al.
DEVELOPMENTAL CELL (2019)
Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines
Tiziana Tataranni et al.
CELLS (2019)
Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer
Timothy J. Humpton et al.
CANCER DISCOVERY (2019)
Clockophagy is a novel selective autophagy process favoring ferroptosis
Minghua Yang et al.
SCIENCE ADVANCES (2019)
Autophagic degradation of the circadian clock regulator promotes ferroptosis
Jiao Liu et al.
AUTOPHAGY (2019)
Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
Sarbajeet Nagdas et al.
CELL REPORTS (2019)
PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells
Chunle Zhao et al.
FRONTIERS IN PHARMACOLOGY (2019)
Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma
Can Huang et al.
CANCERS (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer
Hyo Won Chang et al.
ONCOGENE (2019)
Enzyme-mediated depletion of L-cyst(e)ine synergizes with thioredoxin reductase inhibition for suppression of pancreatic tumor growth
Sabin Kshattry et al.
NPJ PRECISION ONCOLOGY (2019)
KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer
Andrew M. Waters et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2018)
Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis
H. Helen Lin et al.
AUTOPHAGY (2018)
Lipid metabolism and lipophagy in cancer
Meenu Maan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Oncogene-induced senescence and tumour control in complex biological systems
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice
Xinxin Song et al.
GASTROENTEROLOGY (2018)
Cargo recognition and degradation by selective autophagy
Damian Gatica et al.
NATURE CELL BIOLOGY (2018)
Mechanism and medical implications of mammalian autophagy
Ivan Dikic et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Building and decoding ubiquitin chains for mitophagy
J. Wade Harper et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells
Yu-Huei Liu et al.
PHYTOMEDICINE (2018)
The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose
Xiang Li et al.
CELL DEATH & DISEASE (2018)
Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
Grace R. Anderson et al.
NATURE COMMUNICATIONS (2018)
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and nonautonomous Mechanisms
Annan Yang et al.
CANCER DISCOVERY (2018)
PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
Changfeng Li et al.
DEVELOPMENTAL CELL (2018)
Autophagy-dependent cell death - where, how and why a cell eats itself to death
Shani Bialik et al.
JOURNAL OF CELL SCIENCE (2018)
Parkin and PINK1 mitigate STING-induced inflammation
Danielle A. Sliter et al.
NATURE (2018)
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
Konstantinos Palikaras et al.
NATURE CELL BIOLOGY (2018)
Selective Autophagy and Xenophagy in Infection and Disease
Vartika Sharma et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
Inflammatory signaling cascades and autophagy in cancer
Teresa Monkkonen et al.
AUTOPHAGY (2018)
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Yangchun Xie et al.
GASTROENTEROLOGY (2017)
Mitochondrial Dysfunction: A novel Potential Driver of epithelial-to-Mesenchymal Transition in Cancer
Flora Guerra et al.
FRONTIERS IN ONCOLOGY (2017)
Targeting autophagy in cancer
Jean M. Mulcahy Levy et al.
NATURE REVIEWS CANCER (2017)
Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer
Rui Kang et al.
CELL RESEARCH (2017)
FKBP8 recruits LC3A to mediate Parkin-independent mitophagy
Zambarlal Bhujabal et al.
EMBO REPORTS (2017)
HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Shan Zhu et al.
CANCER RESEARCH (2017)
Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Yongjie Wei et al.
CELL (2017)
A novel PINK1-and PARK2-dependent protective neuroimmune pathway in lethal sepsis
Rui Kang et al.
AUTOPHAGY (2016)
Autophagy promotes ferroptosis by degradation of ferritin
Wen Hou et al.
AUTOPHAGY (2016)
p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation
Wei Jing Liu et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2016)
The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway
Raymonde Szargel et al.
HUMAN MOLECULAR GENETICS (2016)
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
Lena Seifert et al.
NATURE (2016)
The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes KrasG12D-mediated pancreatic cancer initiation
C. Loncle et al.
CELL DEATH & DISEASE (2016)
Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation
Shenghong Yang et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Autophagy is required for PDAC glutamine metabolism
Ju-Won Seo et al.
SCIENTIFIC REPORTS (2016)
Deubiquitinating enzymes regulate PARK2-mediated mitophagy
Yuqing Wang et al.
AUTOPHAGY (2015)
p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
Yoshinori Katsuragi et al.
FEBS JOURNAL (2015)
The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway
Feng Gao et al.
HUMAN MOLECULAR GENETICS (2015)
BNIP3-and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory
Timothy E. O'Sullivan et al.
IMMUNITY (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
Tomokazu Murakawa et al.
NATURE COMMUNICATIONS (2015)
Posttranslational modification of autophagy-related proteins in macroautophagy
Yangchun Xie et al.
AUTOPHAGY (2015)
HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice
Hikaru Ito et al.
EMBO MOLECULAR MEDICINE (2015)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
Douglas R. Green et al.
CELL (2014)
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
Yvette C. Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
Jina Yun et al.
ELIFE (2014)
Eat-Me: Autophagy, Phagocytosis, and Reactive Oxygen Species Signaling
Philip J. Vernon et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Targeting apoptosis pathways in pancreatic cancer
Alexander Arlt et al.
CANCER LETTERS (2013)
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2013)
Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
Min Fu et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
p53 status determines the role of autophagy in pancreatic tumour development
Mathias T. Rosenfeldt et al.
NATURE (2013)
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
Charleen T. Chu et al.
NATURE CELL BIOLOGY (2013)
Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration
R. Palorini et al.
ONCOGENE (2013)
Prognostic Significance of Autophagy-Related Protein Expression in Resected Pancreatic Ductal Adenocarcinoma
Yoon Ho Ko et al.
PANCREAS (2013)
p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
Kristen M. Livesey et al.
CANCER RESEARCH (2012)
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
Lei Liu et al.
NATURE CELL BIOLOGY (2012)
The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia
Rui Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control
Daolin Tang et al.
CELL METABOLISM (2011)
Image-based genome-wide siRNA screen identifies selective autophagy factors
Anthony Orvedahl et al.
NATURE (2011)
Oxidative stress, inflammation, and cancer How are they linked?
Simone Reuter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Endogenous HMGB1 regulates autophagy
Daolin Tang et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
Urmi Bandyopadhyay et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
NATURE (2008)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)