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DDAH1 Deficiency Attenuates Endothelial Cell Cycle Progression and Angiogenesis
Ping Zhang et al.
PLOS ONE (2013)
Ablation of SGK1 Impairs Endothelial Cell Migration and Tube Formation Leading to Decreased Neo-Angiogenesis Following Myocardial Infarction
Elham Zarrinpashneh et al.
PLOS ONE (2013)
The p130 Isoform of Angiomotin Is Required for Yap-Mediated Hepatic Epithelial Cell Proliferation and Tumorigenesis
Chunling Yi et al.
SCIENCE SIGNALING (2013)
Impact of breast cancer surgery on angiogenesis circulating biomarkers: a prospective longitudinal study
Georgios K. Georgiou et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2013)
Eph Receptor Signaling and Ephrins
Erika M. Lisabeth et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
The Hippo pathway and human cancer
Kieran F. Harvey et al.
NATURE REVIEWS CANCER (2013)
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Fa-Xing Yu et al.
CELL (2012)
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Joseph Rosenbluh et al.
CELL (2012)
Role of TAZ as Mediator of Wnt Signaling
Luca Azzolin et al.
CELL (2012)
Down-regulation of CXCL1 inhibits tumor growth in colorectal liver metastasis
Obul R. Bandapalli et al.
CYTOKINE (2012)
Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber
Ulrike Haessler et al.
INTEGRATIVE BIOLOGY (2012)
Biology of the apelin-APJ axis in vascular formation
Hiroyasu Kidoya et al.
JOURNAL OF BIOCHEMISTRY (2012)
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling
Moritz Felcht et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Survivin promotes glioma angiogenesis through vascular endothelial growth factor and basic fibroblast growth factor in vitro and in vivo
Peng Wang et al.
MOLECULAR CARCINOGENESIS (2012)
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
Yuhui Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Vascular Normalization as a Therapeutic Strategy for Malignant and Nonmalignant Disease
Shom Goel et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis
Kenneth E. Lipson et al.
FIBROGENESIS & TISSUE REPAIR (2012)
Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells
Roberta Mazzieri et al.
CANCER CELL (2011)
The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells
Michelangelo Cordenonsi et al.
CELL (2011)
CCN1/CYR61: the very model of a modern matricellular protein
Lester F. Lau
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Hippo pathway regulation by cell morphology and stress fibers
Ken-Ichi Wada et al.
DEVELOPMENT (2011)
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
Bin Zhao et al.
GENES & DEVELOPMENT (2011)
Angiomotin-like Proteins Associate with and Negatively Regulate YAP1
Wenqi Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin
Siew Wee Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis
Yeqi Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Molecular mechanisms and clinical applications of angiogenesis
Peter Carmeliet et al.
NATURE (2011)
Tumor angiogenesis: molecular pathways and therapeutic targets
Sara M. Weis et al.
NATURE MEDICINE (2011)
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
M. Z. Xu et al.
ONCOGENE (2011)
NORMALIZATION OF THE VASCULATURE FOR TREATMENT OF CANCER AND OTHER DISEASES
Shom Goel et al.
PHYSIOLOGICAL REVIEWS (2011)
Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK)
Guorong Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Emerging Role of Apelin as a Therapeutic Target in Cancer: A Patent Review
Srujana Rayalam et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2011)
Targeting hypoxia in cancer therapy
William R. Wilson et al.
NATURE REVIEWS CANCER (2011)
Pericytes and vessel maturation during tumor angiogenesis and metastasis
Ahmad Raza et al.
AMERICAN JOURNAL OF HEMATOLOGY (2010)
A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein
Snezana Kojic et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Connective tissue growth factor is a substrate of ADAM28
Satsuki Mochizuki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Isolated tumor endothelial cells maintain specific character during long-term culture
Kohei Matsuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
DLC1 Negatively Regulates Angiogenesis in a Paracrine Fashion
Yi-Ping Shih et al.
CANCER RESEARCH (2010)
The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
Xaralabos Varelas et al.
DEVELOPMENTAL CELL (2010)
Serum and Glucocorticoid-Inducible Kinase 1 (SGK1) Is Necessary for Vascular Remodeling During Angiogenesis
Catarina Catela et al.
DEVELOPMENTAL DYNAMICS (2010)
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors
Rachel Ma Linger et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
Expression Profiling of ETS and MMP Factors in VEGF-Activated Endothelial Cells: Role of MMP-10 in VEGF-Induced Angiogenesis
Sun-Hee Heo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Apelin Expression in Human Non-small Cell Lung Cancer Role in Angiogenesis and Prognosis
Judit Berta et al.
JOURNAL OF THORACIC ONCOLOGY (2010)
Role of Angiopoietin-2 in Regulating Growth and Vascularity of Astrocytomas
Gelareh Zadeh et al.
JOURNAL OF ONCOLOGY (2010)
Targeting the tumour vasculature: insights from physiological angiogenesis
Alicia S. Chung et al.
NATURE REVIEWS CANCER (2010)
The role of the Angiopoietins in vascular morphogenesis
Markus Thomas et al.
ANGIOGENESIS (2009)
VEGFRs and Notch: a dynamic collaboration in vascular patterning
Lars Jakobsson et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
Marta Paez-Ribes et al.
CANCER CELL (2009)
Both TEAD-Binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-Associated Protein
Bin Zhao et al.
CANCER RESEARCH (2009)
VE-Cadherin-Mediated Cell-Cell Interaction Suppresses Sprouting via Signaling to MLC2 Phosphorylation
Sabu Abraham et al.
CURRENT BIOLOGY (2009)
TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
Heng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Thymidine Kinase 1 and Thymidine Phosphorylase Expression in Non-Small-cell Lung Carcinoma in Relation to Angiogenesis and Proliferation
J. Scott Brockenbrough et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2009)
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation
Rosario Amato et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
Hellmut G. Augustin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Ect2 links the PKCι-Par6α complex to Rac1 activation and cellular transformation
V. Justilien et al.
ONCOGENE (2009)
Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis
Y. Li et al.
ONCOGENE (2009)
Endoglin in angiogenesis and vascular diseases
Peter ten Dijke et al.
ANGIOGENESIS (2008)
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
Maria Praskova et al.
CURRENT BIOLOGY (2008)
Premenstrual regulation of the pro-angiogenic factor CYR61 in human endometrium
Isabella Gashaw et al.
ENDOCRINOLOGY (2008)
TEAD mediates YAP-dependent gene induction and growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2008)
Deleted in liver cancer-1 (DLC-1): A tumor suppressor not just for liver
Yi-Chun Liao et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
The role of adherens junctions and VE-cadherin in the control of vascular permeability
Elisabetta Dejana et al.
JOURNAL OF CELL SCIENCE (2008)
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
Xaralabos Varelas et al.
NATURE CELL BIOLOGY (2008)
STAT3: A critical transcription activator in angiogenesis
Zhong Chen et al.
MEDICINAL RESEARCH REVIEWS (2008)
Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: Correlation with the angiogenesis and clinical outcome
Zhe Shao et al.
ORAL ONCOLOGY (2008)
Modes of resistance to anti-angiogenic therapy
Gabriele Bergers et al.
NATURE REVIEWS CANCER (2008)
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
Kathy Miller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Apelin is a potent activator of tumour neoangiogenesis
S. C. Sorli et al.
ONCOGENE (2007)
Tumour vascularization: sprouting angiogenesis and beyond
Femke Hillen et al.
CANCER AND METASTASIS REVIEWS (2007)
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2007)
Angiopoietin: A TIE(d) balance in tumor angiogenesis
Winston S. N. Shim et al.
MOLECULAR CANCER RESEARCH (2007)
Genes that distinguish physiological and pathological angiogenesis
Steven Seaman et al.
CANCER CELL (2007)
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis
Roland E. Kaelin et al.
DEVELOPMENTAL BIOLOGY (2007)
The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis
Tanju G. Nacak et al.
CIRCULATION RESEARCH (2007)
Crim1(KST264/KST264) mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development
Lorine Wilkinson et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
DLC-1: a Rho GTPase-activating protein and tumour suppressor
Marian E. Durkin et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2007)
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
Alan Sandler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin
Julie Gavard et al.
NATURE CELL BIOLOGY (2006)
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells
Christopher Daly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
Michael R. Mancuso et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway
Benedetta Bussolati et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer
DZ Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth
N Kertesz et al.
BLOOD (2006)
Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression
M Héroult et al.
EXPERIMENTAL CELL RESEARCH (2006)
EphB4 controls blood vascular morphogenesis during postnatal angiogenesis
R Erber et al.
EMBO JOURNAL (2006)
Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model
Matthias Hofmann et al.
NEOPLASIA (2006)
Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation
U Fiedler et al.
NATURE MEDICINE (2006)
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
M Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Multiple roles for the receptor tyrosine kinase Axl in tumor formation
SJ Holland et al.
CANCER RESEARCH (2005)
Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis
F Yang et al.
CANCER RESEARCH (2005)
Pathophysiological consequences of VEGF-induced vascular permeability
SM Weis et al.
NATURE (2005)
Magic roundabout, a tumor endothelial marker: Expression and signaling
P Seth et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis
M Presta et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
EH Chan et al.
ONCOGENE (2005)
Different effects of angiopoietin-2 in different vascular beds in the eye: new vessels are most sensitive
Y Oshima et al.
FASEB JOURNAL (2005)
Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor
M Gallicchio et al.
BLOOD (2005)
The Tie-2 ligand Angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism
M Scharpfenecker et al.
JOURNAL OF CELL SCIENCE (2005)
DLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic development
ME Durkin et al.
FEBS LETTERS (2005)
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
DJ Hicklin et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Cellular abnormalities of blood vessels as targets in cancer
P Baluk et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
CARP, a cardiac ankyrin repeat protein, is up-regulated during wound healing and induces angiogenesis in experimental granulation tissue
Y Shi et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A1
P Scapini et al.
JOURNAL OF IMMUNOLOGY (2004)
EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation
DM Brantley-Sieders et al.
JOURNAL OF CELL SCIENCE (2004)
Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth
NK Noren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
CXC chemokines: the regulatory link between inflammation and angiogenesis
P Romagnani et al.
TRENDS IN IMMUNOLOGY (2004)
Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation
S Saito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist
P Dobrzanski et al.
CANCER RESEARCH (2004)
TGF-β induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways
T Nakagawa et al.
KIDNEY INTERNATIONAL (2004)
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
H Hurwitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
N Tang et al.
CANCER CELL (2004)
Angiopoietin-2 enhances retinal vessel sensitivity to vascular endothelial growth factor
Y Oshima et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis
S Weis et al.
JOURNAL OF CELL BIOLOGY (2004)
Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction
F Lebrin et al.
EMBO JOURNAL (2004)
The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1
B Degryse et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Powerful and controllable angiogenesis by using gene-modified cells expressing human hepatocyte growth factor and thymidine kinase
Y Hisaka et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
G Thurston
CELL AND TISSUE RESEARCH (2003)
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity
B Wang et al.
CANCER CELL (2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
H Gerhardt et al.
JOURNAL OF CELL BIOLOGY (2003)
Molecular regulation of vessel maturation
RK Jain
NATURE MEDICINE (2003)
Interleukin-17 promotes angiogenesis and tumor growth
M Numasaki et al.
BLOOD (2003)
CYR61 (CCN1) is essential for placental development and vascular integrity
FE Mo et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
CRIM1 is involved in endothelial cell capillary formation in vitro and is expressed in blood vessels in vivo
J Glienke et al.
MECHANISMS OF DEVELOPMENT (2002)
Role of angiogenesis in tumor growth and metastasis
J Folkman
SEMINARS IN ONCOLOGY (2002)
Cyr61 promotes breast tumorigenesis and cancer progression
MS Tsai et al.
ONCOGENE (2002)
Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis
V Kostourou et al.
BRITISH JOURNAL OF CANCER (2002)
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
IB Lobov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Stimulation of angiogenesis by Cyr61 gene: A new therapeutic candidate
V Fataccioli et al.
HUMAN GENE THERAPY (2002)
Activation of the Tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth
T Hawighorst et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
GL Niu et al.
ONCOGENE (2002)
Breast cancer -: Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease
D Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Urokinase/urokinase receptor and vitronectin/αvβ3 integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways
B Degryse et al.
ONCOGENE (2001)
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
K Ogawa et al.
ONCOGENE (2000)
Angiogenesis in cancer and other diseases
P Carmeliet et al.
NATURE (2000)
Openings between defective endothelial cells explain tumor vessel leakiness
H Hashizume et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Control of apoptosis during angiogenesis by survivin expression in endothelial cells
DS O'Connor et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)