Related references
Note: Only part of the references are listed.Three-dimensional bioprinted hepatorganoids prolong survival of mice with liver failure
Huayu Yang et al.
GUT (2021)
Three-dimensional bio-printing of primary human hepatocellular carcinoma for personalized medicine
Feihu Xie et al.
BIOMATERIALS (2021)
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Yuling Han et al.
NATURE (2021)
An Engineered Tumor-on-a-Chip Device with Breast Cancer-Immune Cell Interactions for Assessing T-cell Recruitment
Aereas Aung et al.
CANCER RESEARCH (2020)
Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer
Ruoshi Shi et al.
CLINICAL CANCER RESEARCH (2020)
Cell swelling, softening and invasion in a three-dimensional breast cancer model
Yu Long Han et al.
NATURE PHYSICS (2020)
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
Fadi Jacob et al.
CELL (2020)
Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment
Karen Hoffmann et al.
EMBO JOURNAL (2020)
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
Haibo Zhang et al.
INTENSIVE CARE MEDICINE (2020)
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen et al.
LANCET (2020)
Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China
Wenhua Liang et al.
LANCET ONCOLOGY (2020)
Organoid models of gastrointestinal cancers in basic and translational research
Harry Cheuk Hay Lau et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
Mapping the structure and biological functions within mesenchymal bodies using microfluidics
Sebastien Sart et al.
SCIENCE ADVANCES (2020)
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
Anna Herland et al.
NATURE BIOMEDICAL ENGINEERING (2020)
Open-source, 3D-printed Peristaltic Pumps for Small Volume Point-of-Care Liquid Handling
Michael R. Behrens et al.
SCIENTIFIC REPORTS (2020)
Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids
Victor Hernandez-Gordillo et al.
BIOMATERIALS (2020)
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
Vanessa Monteil et al.
CELL (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
Palladium(II)-η3-Allyl Complexes BearingN-TrifluoromethylN-Heterocyclic Carbenes: A New Generation of Anticancer Agents that Restrain the Growth of High-Grade Serous Ovarian Cancer Tumoroids
Thomas Scattolin et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors
Melissa Bersanelli
IMMUNOTHERAPY (2020)
The epidemiology, diagnosis and treatment of COVID-19
Pan Zhai et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)
Metal oxides based electrochemical pH sensors: Current progress and future perspectives
Libu Manjakkal et al.
PROGRESS IN MATERIALS SCIENCE (2020)
SARS-CoV-2 productively infects human gut enterocytes
Mart M. Lamers et al.
SCIENCE (2020)
Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids
Bing Zhao et al.
PROTEIN & CELL (2020)
Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells
Xingru Li et al.
CANCERS (2020)
Infection of bat and human intestinal organoids by SARS-CoV-2
Zhou Jie et al.
NATURE MEDICINE (2020)
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
SCIENCE IMMUNOLOGY (2020)
Early predictors of clinical outcomes of COVID-19 outbreak in Milan, Italy
Fabio Ciceri et al.
CLINICAL IMMUNOLOGY (2020)
Screening Cancer Immunotherapy: When Engineering Approaches Meet Artificial Intelligence
Xingwu Zhou et al.
ADVANCED SCIENCE (2020)
Mechano-modulatory synthetic niches for liver organoid derivation
Giovanni Sorrentino et al.
NATURE COMMUNICATIONS (2020)
Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids
Brooke Schuster et al.
NATURE COMMUNICATIONS (2020)
Bioengineered in Vitro Tissue Models to Study SARS-CoV-2 Pathogenesis and Therapeutic Validation
Juhi Chakraborty et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)
Microfluidic devices for the detection of viruses: aspects of emergency fabrication during the COVID-19 pandemic and other outbreaks
Jose Alvim Berkenbrock et al.
PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2020)
Multi-corneal barrier-on-a-chip to recapitulate eye blinking shear stress forces
Rodi Abdalkader et al.
LAB ON A CHIP (2020)
mu Pump: An open-source pressure pump for precision fluid handling in microfluidics
Run Ze Gao et al.
HARDWAREX (2020)
Stem cell-based Lung-on-Chips: The best of both worlds?
Janna C. Nawroth et al.
ADVANCED DRUG DELIVERY REVIEWS (2019)
An air-chamber-based microfluidic stabilizer for attenuating syringe-pump-induced fluctuations
Zeheng Jiao et al.
MICROFLUIDICS AND NANOFLUIDICS (2019)
Flow-enhanced vascularization and maturation of kidney organoids in vitro
Kimberly A. Homan et al.
NATURE METHODS (2019)
Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output
Stefano L. Giandomenico et al.
NATURE NEUROSCIENCE (2019)
Modeling Patient-Derived Glioblastoma with Cerebral Organoids
Amanda Linkous et al.
CELL REPORTS (2019)
Engineering Microfluidic Organoid-on-a-Chip Platforms
Fang Yu et al.
MICROMACHINES (2019)
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity
Oded Kopper et al.
NATURE MEDICINE (2019)
Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids
M. Porotto et al.
MBIO (2019)
Application of Cancer Organoid Model for Drug Screening and Personalized Therapy
Jumpei Kondo et al.
CELLS (2019)
Current Status of Patient-Derived Ovarian Cancer Models
Yoshiaki Maru et al.
CELLS (2019)
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
Silvia Velasco et al.
NATURE (2019)
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Ela Elyada et al.
CANCER DISCOVERY (2019)
Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture
Joo Hyun Jee et al.
STEM CELLS INTERNATIONAL (2019)
Microfluidic Modules with Integrated Solid-State Sensors for Reconfigurable Miniaturized Analysis Systems
Pablo Gimenez-Gomez et al.
ACS OMEGA (2019)
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening
Matteo Boretto et al.
NATURE CELL BIOLOGY (2019)
Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
Kevin Achberger et al.
ELIFE (2019)
Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury
Shuyong Wang et al.
CELL RESEARCH (2019)
Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening
Minsuh Kim et al.
NATURE COMMUNICATIONS (2019)
Recent Advances in Body-on-a-Chip Systems
Jong Hwan Sung et al.
ANALYTICAL CHEMISTRY (2019)
Zika Virus as Oncolytic Therapy for Brain Cancer: Myth or Reality?
Kar Yan Su et al.
FRONTIERS IN MICROBIOLOGY (2019)
iPSCs-Based Neural 3D Systems: A Multidimensional Approach for Disease Modeling and Drug Discovery
Gianluca Costamagna et al.
CELLS (2019)
A multi-site metastasis-on-a-chip microphysiological system for assessing metastatic preference of cancer cells
Julio Aleman et al.
BIOTECHNOLOGY AND BIOENGINEERING (2019)
Long-term expanding human airway organoids for disease modeling
Norman Sachs et al.
EMBO JOURNAL (2019)
Evaluation of variability in human kidney organoids
Belinda Phipson et al.
NATURE METHODS (2019)
Emerging organoid models: leaping forward in cancer research
Han Fan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Microfluidic chip system integrated with light addressable potentiometric sensor (LAPS) for real-time extracellular acidification detection
Tao Liang et al.
SENSORS AND ACTUATORS B-CHEMICAL (2019)
Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient-Derived Xenografts, and Three-Dimensional Culture of Patient-Derived Cells
Takeshi Namekawa et al.
CELLS (2019)
An Effective Multi-Stage Liposomal DNA Origami Nanosystem for In Vivo Cancer Therapy
Stefano Palazzolo et al.
CANCERS (2019)
Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy
Marinke W. van der Helm et al.
LAB ON A CHIP (2019)
Characterization of organoid cultured human breast cancer
Nadine Goldhammer et al.
BREAST CANCER RESEARCH (2019)
A one-stop microfluidic-based lung cancer organoid culture platform for testing drug sensitivity
Da Jung Jung et al.
LAB ON A CHIP (2019)
Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids
Zachary Richards et al.
ISCIENCE (2019)
Tumour heterogeneity and resistance to cancer therapies
Ibiayi Dagogo-Jack et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Vascularized Liver Organoids Generated Using Induced Hepatic Tissue and Dynamic Liver-Specific Microenvironment as a Drug Testing Platform
Yoonhee Jin et al.
ADVANCED FUNCTIONAL MATERIALS (2018)
Nanoliter Cell Culture Array with Tunable Chemical Gradients
Jonathan Avesar et al.
ANALYTICAL CHEMISTRY (2018)
A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
Norman Sachs et al.
CELL (2018)
Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer
Suk Hyung Lee et al.
CELL (2018)
Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
Takashi Seino et al.
CELL STEM CELL (2018)
Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policies
Laura Pimpin et al.
JOURNAL OF HEPATOLOGY (2018)
A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function
Xiaolin Wang et al.
LAB ON A CHIP (2018)
A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood-retinal barrier
Jose Yeste et al.
LAB ON A CHIP (2018)
Human brain organoid-on-a-chip to model prenatal nicotine exposure
Yaqing Wang et al.
LAB ON A CHIP (2018)
Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens
Bastien Laperrousaz et al.
NUCLEIC ACIDS RESEARCH (2018)
Differentiated human airway organoids to assess infectivity of emerging influenza virus
Jie Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
Georgios Vlachogiannis et al.
SCIENCE (2018)
A Spontaneous 3D Bone-On-a-Chip for Bone Metastasis Study of Breast Cancer Cells
Sijie Hao et al.
SMALL (2018)
In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening
Andrea R. Mazzocchi et al.
SCIENTIFIC REPORTS (2018)
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
Sigrid A. Langhans
FRONTIERS IN PHARMACOLOGY (2018)
Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors
Tyler DiStefano et al.
STEM CELL REPORTS (2018)
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
Krijn K. Dijkstra et al.
CELL (2018)
Millifluidic culture improves human midbrain organoid vitality and differentiation
Emanuel Berger et al.
LAB ON A CHIP (2018)
Human stomach-on-a-chip with luminal flow and peristaltic-like motility
Kang Kug Lee et al.
LAB ON A CHIP (2018)
Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate
Qi Chen et al.
MBIO (2018)
Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids
Sarah J. Hill et al.
CANCER DISCOVERY (2018)
Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies
Sandro Nuciforo et al.
CELL REPORTS (2018)
Organoid Modeling of the Tumor Immune Microenvironment
James T. Neal et al.
CELL (2018)
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
Huili Hu et al.
CELL (2018)
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening
Helen H. N. Yang et al.
CELL STEM CELL (2018)
Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity
Noriaki Tanaka et al.
ORAL ONCOLOGY (2018)
TGF-β induced epithelial-mesenchymal transition in an advanced cervical tumor model by 3D printing
Y. Pang et al.
BIOFABRICATION (2018)
Differentiation of Induced Pluripotent Stem Cells (iPSC) into human bronchial epithelium from healthy and severe COPD patients.
Engi Ahmed et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips
Michael J. Workman et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2018)
Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids
Venktesh S. Shirure et al.
LAB ON A CHIP (2018)
In situ differentiation and generation of functional liver organoids from human iPSCs in a 3D perfusable chip system
Yaqing Wang et al.
LAB ON A CHIP (2018)
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
Daniel Ohlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Zika virus has oncolytic activity against glioblastoma stem cells
Zhe Zhu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
A three-dimensional model of human lung development and disease from pluripotent stem cells
Ya-Wen Chen et al.
NATURE CELL BIOLOGY (2017)
Human primary liver cancer-derived organoid cultures for disease modeling and drug screening
Laura Broutier et al.
NATURE MEDICINE (2017)
Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors
Yu Shrike Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication
Pavithra L. Chavali et al.
SCIENCE (2017)
Lateral trapezoid microfluidic platform for investigating mechanotransduction of cells to spatial shear stress gradients
Rebecca Soffe et al.
SENSORS AND ACTUATORS B-CHEMICAL (2017)
Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal Cancer
Alba Cristobal et al.
CELL REPORTS (2017)
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro
Bryan A. Hassell et al.
CELL REPORTS (2017)
Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses
Laurent Meertens et al.
CELL REPORTS (2017)
Humans in a Dish: The Potential of Organoids in Modeling Immunity and Infectious Diseases
Nino Iakobachvili et al.
FRONTIERS IN MICROBIOLOGY (2017)
Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
Hung-Ju Chiang et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2017)
Intestine-on-a-Chip Microfluidic Model for Efficient in Vitro Screening of Oral Chemotherapeutic Uptake
Kyall Pocock et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Intestine-on-a-Chip Microfluidic Model for Efficient in Vitro Screening of Oral Chemotherapeutic Uptake
Kyall Pocock et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)
Three-Dimensional Cell Cultures in Drug Discovery and Development
Ye Fang et al.
SLAS DISCOVERY (2017)
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform
Aleksander Skardal et al.
SCIENTIFIC REPORTS (2017)
A pump-free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte-like cells
Louis Jun Ye Ong et al.
BIOTECHNOLOGY AND BIOENGINEERING (2017)
Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels
Norman Sachs et al.
DEVELOPMENT (2017)
Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
Heather A. McCauley et al.
DEVELOPMENT (2017)
The Microenvironmental Landscape of Brain Tumors
Daniela F. Quail et al.
CANCER CELL (2017)
The bioink: A comprehensive review on bioprintable materials
Monika Hospodiuk et al.
BIOTECHNOLOGY ADVANCES (2017)
Design and Construction of a Multi-Organ Microfluidic Chip Mimicking the in vivo Microenvironment of Lung Cancer Metastasis
Zhiyun Xu et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip
Yu Shrike Zhang et al.
BIOMATERIALS (2016)
A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Christopher G. Hubert et al.
CANCER RESEARCH (2016)
Modeling Development and Disease with Organoids
Hans Clevers
CELL (2016)
Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection
Michael F. Wells et al.
CELL STEM CELL (2016)
A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis
Masayuki Fujii et al.
CELL STEM CELL (2016)
Organoid Models of Human Gastrointestinal Development and Disease
Priya H. Dedhia et al.
GASTROENTEROLOGY (2016)
Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues
Anna Marsano et al.
LAB ON A CHIP (2016)
Surface-tension driven open microfluidic platform for hanging droplet culture
T. E. de Groot et al.
LAB ON A CHIP (2016)
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels
Xiaolin Wang et al.
LAB ON A CHIP (2016)
The Brazilian Zika virus strain causes birth defects in experimental models
Fernanda R. Cugola et al.
NATURE (2016)
Designer matrices for intestinal stem cell and organoid culture
Nikolce Glorevski et al.
NATURE (2016)
Organoids as an in vitro model of human development and disease
Aliya Fatehullah et al.
NATURE CELL BIOLOGY (2016)
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
Laura Broutier et al.
NATURE PROTOCOLS (2016)
Zika virus impairs growth in human neurospheres and brain organoids
Patricia P. Garcez et al.
SCIENCE (2016)
Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes
George Eng et al.
NATURE COMMUNICATIONS (2016)
Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
Jennifer Quantius et al.
PLOS PATHOGENS (2016)
Polymer Microfluidics: Simple, Low-Cost Fabrication Process Bridging Academic Lab Research to Commercialized Production
Chia-Wen Tsao
MICROMACHINES (2016)
Investigating Nonalcoholic Fatty Liver Disease in a Liver-on-a-Chip Microfluidic Device
Manuele Gori et al.
PLOS ONE (2016)
Skin-on-a-chip model simulating inflammation, edema and drug-based treatment
Maierdanjiang Wufuer et al.
SCIENTIFIC REPORTS (2016)
Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip
Sejoong Kim et al.
BIOFABRICATION (2016)
Rapid 3D Extrusion of Synthetic Tumor Microenvironments
Joshua M. Grolman et al.
ADVANCED MATERIALS (2015)
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
Jacquelyn A. Brown et al.
BIOMICROFLUIDICS (2015)
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
Marc van de Wetering et al.
CELL (2015)
Organoid Models of Human and Mouse Ductal Pancreatic Cancer
Sylvia F. Boj et al.
CELL (2015)
Quantification of regenerative potential in primary human mammary epithelial cells
Jelena R. Linnemann et al.
DEVELOPMENT (2015)
Modeling mouse and human development using organoid cultures
Meritxell Huch et al.
DEVELOPMENT (2015)
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Ilka Maschmeyer et al.
LAB ON A CHIP (2015)
A lung-on-a-chip array with an integrated bio-inspired respiration mechanism
Andreas O. Stucki et al.
LAB ON A CHIP (2015)
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
Minoru Takasato et al.
NATURE (2015)
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids
Ling Huang et al.
NATURE MEDICINE (2015)
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids
Mami Matano et al.
NATURE MEDICINE (2015)
Organs-on-chips at the frontiers of drug discovery
Eric W. Esch et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids
Mirjana Kessler et al.
NATURE COMMUNICATIONS (2015)
Optimizing Wnt-3a and R-spondin1 concentrations for stem cell renewal and differentiation in intestinal organoids using a gradient-forming microdevice
Asad A. Ahmad et al.
RSC ADVANCES (2015)
Design and Characterization of a Sensorized Microfluidic Cell-Culture System with Electro-Thermal Micro-Pumps and Sensors for Cell Adhesion, Oxygen, and pH on a Glass Chip
Sebastian M. Bonk et al.
BIOSENSORS-BASEL (2015)
Application of ion-sensitive field effect transistors for ion channel screening
Kenneth B. Walsh et al.
BIOSENSORS & BIOELECTRONICS (2014)
Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature
Matthew Biggerstaff et al.
BMC INFECTIOUS DISEASES (2014)
Organoid Cultures Derived from Patients with Advanced Prostate Cancer
Dong Gao et al.
CELL (2014)
Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures
Wouter R. Karthaus et al.
CELL (2014)
Real-time feedback control of pH within microfluidics using integrated sensing and actuation
David Welch et al.
LAB ON A CHIP (2014)
Microfluidic organs-on-chips
Sangeeta N. Bhatia et al.
NATURE BIOTECHNOLOGY (2014)
3D bioprinting of tissues and organs
Sean V. Murphy et al.
NATURE BIOTECHNOLOGY (2014)
The hepatitis B virus-associated tumor microenvironment in hepatocellular carcinoma
Pengyuan Yang et al.
NATIONAL SCIENCE REVIEW (2014)
A novel microphysiometer based on high sensitivity LAPS and microfluidic system for cellular metabolism study and rapid drug screening
Ning Hu et al.
BIOSENSORS & BIOELECTRONICS (2013)
Advances in Microfluidic Materials, Functions, Integration, and Applications
Pamela N. Nge et al.
CHEMICAL REVIEWS (2013)
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
Meritxell Huch et al.
EMBO JOURNAL (2013)
Annual Report to the Nation on the Status of Cancer, 19752009, Featuring the Burden and Trends in Human Papillomavirus (HPV)Associated Cancers and HPV Vaccination Coverage Levels
Ahmedin Jemal et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Microfluidic heart on a chip for higher throughput pharmacological studies
Ashutosh Agarwal et al.
LAB ON A CHIP (2013)
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
Meritxell Huch et al.
NATURE (2013)
Vascularized and functional human liver from an iPSC-derived organ bud transplant
Takanori Takebe et al.
NATURE (2013)
Cerebral organoids model human brain development and microcephaly
Madeline A. Lancaster et al.
NATURE (2013)
Microfabrication of human organs-on-chips
Dongeun Huh et al.
NATURE PROTOCOLS (2013)
Real-time optical pH measurement in a standard microfluidic cell culture system
Einar B. Magnusson et al.
BIOMEDICAL OPTICS EXPRESS (2013)
Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland Organogenesis
Vicki Plaks et al.
CELL REPORTS (2013)
Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells
Maisam Makarem et al.
PLOS BIOLOGY (2013)
Hepatitis B virus-induced hepatocellular carcinoma: The role of the virus x protein
M. Motavaf et al.
ACTA VIROLOGICA (2013)
Controlled formation of heterotypic hepatic micro-organoids in anisotropic hydrogel microfibers for long-term preservation of liver-specific functions
Masumi Yamada et al.
BIOMATERIALS (2012)
Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells
Tyler A. Longmire et al.
CELL STEM CELL (2012)
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
Yi Liu-Chittenden et al.
GENES & DEVELOPMENT (2012)
Deconstructing the third dimension - how 3D culture microenvironments alter cellular cues
Brendon M. Baker et al.
JOURNAL OF CELL SCIENCE (2012)
Cyclic AMP regulates formation of mammary epithelial acini in vitro
Pavel I. Nedvetsky et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering
Ahmed Alrifaiy et al.
POLYMERS (2012)
Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device
Yosuke Nakao et al.
BIOMICROFLUIDICS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
Toshiro Sato et al.
GASTROENTEROLOGY (2011)
Subregional Specification of Embryonic Stem Cell-Derived Ventral Telencephalic Tissues by Timed and Combinatory Treatment with Extrinsic Signals
Teruko Danjo et al.
JOURNAL OF NEUROSCIENCE (2011)
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
Wim de Lau et al.
NATURE (2011)
A Rapid and Simple Procedure for the Establishment of Human Normal and Cancer Renal Primary Cell Cultures from Surgical Specimens
Maria Joao Valente et al.
PLOS ONE (2011)
Pluripotent Stem Cells for the Study of CNS Development
Timothy J. Petros et al.
Frontiers in Molecular Neuroscience (2011)
Rethinking ovarian cancer: recommendations for improving outcomes
Sebastian Vaughan et al.
NATURE REVIEWS CANCER (2011)
The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor
Aleksander Skardal et al.
BIOMATERIALS (2010)
Design and prototyping of a chip-based multi-micro-organoid culture system for substance testing, predictive to human (substance) exposure
Frank Sonntag et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh et al.
SCIENCE (2010)
High throughput, non-invasive and dynamic toxicity screening on adherent cells using respiratory measurements
Simone Beckers et al.
TOXICOLOGY IN VITRO (2010)
A Noninvasive Thin Film Sensor for Monitoring Oxygen Tension during in Vitro Cell Culture
Peter C. Thomas et al.
ANALYTICAL CHEMISTRY (2009)
SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma
Myung Jin Son et al.
CELL STEM CELL (2009)
The microfluidic palette: A diffusive gradient generator with spatio-temporal control
Javier Atencia et al.
LAB ON A CHIP (2009)
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
NATURE (2009)
Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient
Joong Yull Park et al.
STEM CELLS (2009)
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
NATURE (2007)
Microfluidic chip integrated with amperometric detector array for in situ estimating oxygen consumption characteristics of single bovine embryos
Ching-Chou Wu et al.
SENSORS AND ACTUATORS B-CHEMICAL (2007)
Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development
Valerie A. McLin et al.
DEVELOPMENT (2007)
Online monitoring of cell metabolism for studying pharmacodynamic effects
Elke Thedinga et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Generation of cerebellar neuron precursors from embryonic stem cells
HL Su et al.
DEVELOPMENTAL BIOLOGY (2006)
FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo
J Dessimoz et al.
MECHANISMS OF DEVELOPMENT (2006)
Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation
XY Zhu et al.
ANALYST (2004)
Current methods for assaying angiogenesis in vitro and in vivo
CA Staton et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2004)
Functional cellular assays with multiparametric silicon sensor chips
M Brischwein et al.
LAB ON A CHIP (2003)
Simultaneous measurement of cellular respiration and acidification with a single CMOS ISFET
M Lehmann et al.
BIOSENSORS & BIOELECTRONICS (2001)