Related references
Note: Only part of the references are listed.Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
Arianna Fumagalli et al.
CELL STEM CELL (2020)
Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
Priscilla Cheung et al.
CELL STEM CELL (2020)
Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance in Colon Cancer
Daisuke Shiokawa et al.
CANCER RESEARCH (2020)
Phenotypic landscape of intestinal organoid regeneration
Ilya Lukonin et al.
NATURE (2020)
Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts
Maartje van der Heijden et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Self-organization and symmetry breaking in intestinal organoid development
Denise Serra et al.
NATURE (2019)
Gut organoids: mini-tissues in culture to study intestinal physiology and disease
Mohammad Almeqdadi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer
Tianzuo Zhan et al.
NATURE COMMUNICATIONS (2019)
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
Rene Jackstadt et al.
CANCER CELL (2019)
Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
Yi Wang et al.
CELL (2019)
The landscape of somatic mutation in normal colorectal epithelial cells
Henry Lee-Six et al.
NATURE (2019)
A rectal cancer organoid platform to study individual responses to chemoradiation
Karuna Ganesh et al.
NATURE MEDICINE (2019)
Non-redundant functions of EMT transcription factors
Marc P. Stemmler et al.
NATURE CELL BIOLOGY (2019)
The pro-tumorigenic host response to cancer therapies
Yuval Shaked
NATURE REVIEWS CANCER (2019)
Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium
Anna M. Nicholson et al.
CELL STEM CELL (2018)
Intestinal organoids for modelling intestinal development and disease
Kathryn L. Fair et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2018)
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer
Kristiaan J. Lenos et al.
NATURE CELL BIOLOGY (2018)
Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
Mark Schmitt et al.
CELL REPORTS (2018)
Targeting minimal residual disease: a path to cure?
Marlise R. Luskin et al.
NATURE REVIEWS CANCER (2018)
DNA replication stress and cancer chemotherapy
Hiroyuki Kitao et al.
CANCER SCIENCE (2018)
ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance
Romana-Rea Begicevic et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Drug Resistance Driven by Cancer Stem Cells and Their Niche
Marta Prieto-Vila et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
Felipe de Sousa e Melo et al.
NATURE (2017)
Visualization and targeting of LGR5+ human colon cancer stem cells
Mariko Shimokawa et al.
NATURE (2017)
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
Tsukasa Shibue et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
Kelley S. Yan et al.
CELL STEM CELL (2017)
A genome editing approach to study cancer stem cells in human tumors
Carme Cortina et al.
EMBO MOLECULAR MEDICINE (2017)
RNA mis-splicing in disease
Marina M. Scotti et al.
NATURE REVIEWS GENETICS (2016)
Cancer Stem Cells: Basic Concepts and Therapeutic Implications
Dany Nassar et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)
Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters
Paul W. Tetteh et al.
CELL STEM CELL (2016)
A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis
Masayuki Fujii et al.
CELL STEM CELL (2016)
CD44: More than a mere stem cell marker
I. Morath et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)
Metastatic colonization by circulating tumour cells
Joan Massague et al.
NATURE (2016)
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
Marc van de Wetering et al.
CELL (2015)
Krt19+/Lgr5- Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine
Samuel Asfaha et al.
CELL STEM CELL (2015)
Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal Cancer
Alexander W. Fender et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Sequential cancer mutations in cultured human intestinal stem cells
Jarno Drost et al.
NATURE (2015)
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids
Mami Matano et al.
NATURE MEDICINE (2015)
CD44 functions in Wnt signaling by regulating LRP6 localization and activation
M. Schmitt et al.
CELL DEATH AND DIFFERENTIATION (2015)
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Nicola Aceto et al.
CELL (2014)
Evolution of the Cancer Stem Cell Model
Antonija Kreso et al.
CELL STEM CELL (2014)
CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
Matilde Todaro et al.
CELL STEM CELL (2014)
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
Allison S. Cleary et al.
NATURE (2014)
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity
Andriy Marusyk et al.
NATURE (2014)
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
Nick Barker
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Cellular Heterogeneity and Molecular Evolution in Cancer
Vanessa Almendro et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 8 (2013)
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Gerald Schwank et al.
CELL STEM CELL (2013)
Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon
Pramudita Ramadhina Prasetyanti et al.
MOLECULAR CANCER (2013)
Intestinal label-retaining cells are secretory precursors expressing Lgr5
Simon J. A. Buczacki et al.
NATURE (2013)
Tumour heterogeneity and cancer cell plasticity
Corbin E. Meacham et al.
NATURE (2013)
Cancer stem cells: The challenges ahead
Jan Paul Medema
NATURE CELL BIOLOGY (2013)
Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury
Norifumi Takeda et al.
PLOS ONE (2013)
Correction: Internalization of Met Requires the Co-Receptor CD44v6 and Its Link to ERM Proteins
Susanne Hasenauer et al.
PLoS One (2013)
Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
Antonija Kreso et al.
SCIENCE (2013)
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
Jeffrey A. Magee et al.
CANCER CELL (2012)
Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas
Arnout G. Schepers et al.
SCIENCE (2012)
Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling
Masahiro Sonoshita et al.
CANCER CELL (2011)
Accurate Reconstruction of the Temporal Order of Mutations in Neoplastic Progression
Kathleen Sprouffske et al.
CANCER PREVENTION RESEARCH (2011)
Tumor Metastasis: Molecular Insights and Evolving Paradigms
Scott Valastyan et al.
CELL (2011)
Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases
Sebastian M. Dieter et al.
CELL STEM CELL (2011)
Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients
Felipe de Sousa e Melo et al.
CELL STEM CELL (2011)
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Anna Merlos-Suarez et al.
CELL STEM CELL (2011)
Universal patterns of stem cell fate in cycling adult tissues
Allon M. Klein et al.
DEVELOPMENT (2011)
CD133 Protein N-Glycosylation Processing Contributes to Cell Surface Recognition of the Primitive Cell Marker AC133 Epitope
Anthony B. Mak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Toshiro Sato et al.
NATURE (2011)
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
Jason R. Spence et al.
NATURE (2011)
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Hua Tian et al.
NATURE (2011)
Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
Jan Paul Medema et al.
NATURE (2011)
Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized
Elsa Quintana et al.
CANCER CELL (2010)
The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation
Kristel Kemper et al.
CANCER RESEARCH (2010)
Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
Hugo J. Snippert et al.
CELL (2010)
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
Roberta Pang et al.
CELL STEM CELL (2010)
Cancer Stem Cells and Self-renewal
Catherine Adell O'Brien et al.
CLINICAL CANCER RESEARCH (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Outlook and adaptation in advanced cancer: a systematic review
Charlotte Wattebot O'Brien et al.
PSYCHO-ONCOLOGY (2010)
Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
Carlos Lopez-Garcia et al.
SCIENCE (2010)
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
NATURE (2009)
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
Shu Zhang et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
L. Vermeulen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Animal cell differentiation patterns suppress somatic evolution
John W. Pepper et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
NATURE (2007)
Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien et al.
NATURE (2007)
Identification and expansion of human colon-cancer-initiating cells
Lucia Ricci-Vitiani et al.
NATURE (2007)
A five-amino-acid peptide blocks Met- and Ron-dependent cell migration
A Matzke et al.
CANCER RESEARCH (2005)
Identification of human brain tumour initiating cells
SK Singh et al.
NATURE (2004)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom et al.
GENES & DEVELOPMENT (2004)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
CD44 is required for two consecutive steps in HGF/c-Met signaling
V Orian-Rousseau et al.
GENES & DEVELOPMENT (2002)
Multidrug resistance in cancer: Role of ATP-dependent transporters
MM Gottesman et al.
NATURE REVIEWS CANCER (2002)
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
T Brabletz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The ABC of APC
NS Fearnhead et al.
HUMAN MOLECULAR GENETICS (2001)
Share Paper
