Related references
Note: Only part of the references are listed.Nucleocytoplasmic transport defects in neurodegeneration - Cause or consequence?
Saskia Hutten et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria
Aaron Burberry et al.
NATURE (2020)
Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72
Qiang Zhu et al.
NATURE NEUROSCIENCE (2020)
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
Jeannie Chew et al.
MOLECULAR NEURODEGENERATION (2019)
C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner
Qiang Shao et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function
Michael R. White et al.
MOLECULAR CELL (2019)
C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo
So Yoen Choi et al.
NATURE NEUROSCIENCE (2019)
C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies
Sarat C. Vatsavayai et al.
ACTA NEUROPATHOLOGICA (2019)
Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology
Alissa L. Nana et al.
ACTA NEUROPATHOLOGICA (2019)
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism
Bart Swinnen et al.
ACTA NEUROPATHOLOGICA (2018)
Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS
Florian Krach et al.
ACTA NEUROPATHOLOGICA (2018)
Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
Ke Zhang et al.
CELL (2018)
C9orf72-associated neurodegeneration in ALS-FTD: breaking new ground in ribosomal RNA and nucleolar dysfunction
Dustin Herrmann et al.
CELL AND TISSUE RESEARCH (2018)
Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model
Amrutha Swaminathan et al.
HUMAN MOLECULAR GENETICS (2018)
The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis
S. Shekar Dukkipati et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
Yong-Jie Zhang et al.
NATURE MEDICINE (2018)
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Yingxiao Shi et al.
NATURE MEDICINE (2018)
Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity
Hannelore Hartmann et al.
LIFE SCIENCE ALLIANCE (2018)
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
Steven Boeynaems et al.
MOLECULAR CELL (2017)
Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration
Yu Ohki et al.
MOLECULAR NEURODEGENERATION (2017)
RNA phase transitions in repeat expansion disorders
Ankur Jain et al.
NATURE (2017)
Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet
P. E. Bunney et al.
PHYSIOLOGY & BEHAVIOR (2017)
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export
Kevin Y. Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
Sarah Mizielinska et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss
Martin H. Schludi et al.
ACTA NEUROPATHOLOGICA (2017)
Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia
Sarat C. Vatsavayai et al.
BRAIN (2016)
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
Kyung-Ha Lee et al.
CELL (2016)
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death
Chantal Sellier et al.
EMBO JOURNAL (2016)
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
Kohsuke Kanekura et al.
HUMAN MOLECULAR GENETICS (2016)
Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling
Janet Ugolino et al.
PLOS GENETICS (2016)
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
Steven Boeynaems et al.
SCIENTIFIC REPORTS (2016)
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy
Johnathan Cooper-Knock et al.
ACTA NEUROPATHOLOGICA (2015)
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
Martin H. Schludi et al.
ACTA NEUROPATHOLOGICA (2015)
FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions
Dejun Yang et al.
ACTA NEUROPATHOLOGICA (2015)
Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity
Zhouteng Tao et al.
HUMAN MOLECULAR GENETICS (2015)
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
Ke Zhang et al.
NATURE (2015)
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
Brian D. Freibaum et al.
NATURE (2015)
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
Ana Jovicic et al.
NATURE NEUROSCIENCE (2015)
C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD
Jacqueline G. O'Rourke et al.
NEURON (2015)
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
Mai Yamakawa et al.
HUMAN MOLECULAR GENETICS (2015)
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
Stephanie May et al.
ACTA NEUROPATHOLOGICA (2014)
TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
Johannes Brettschneider et al.
ACTA NEUROPATHOLOGICA (2014)
Three major nucleolar proteins migrate from nucleolus to nucleoplasm and cytoplasm in root tip cells of Vicia faba L. exposed to aluminum
Rong Qin et al.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2014)
C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
Manal A. Farg et al.
HUMAN MOLECULAR GENETICS (2014)
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
Aaron R. Haeusler et al.
NATURE (2014)
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
Xinmei Wen et al.
NEURON (2014)
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
Sarah Mizielinska et al.
SCIENCE (2014)
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
Ilmin Kwon et al.
SCIENCE (2014)
Sex Differences in the Number and Size of Motoneurons Innervating Rat Medial Gastrocnemius Muscle
B. Mierzejewska-Krzyzowska et al.
ANATOMIA HISTOLOGIA EMBRYOLOGIA (2014)
Stress granules as crucibles of ALS pathogenesis
Yun R. Li et al.
JOURNAL OF CELL BIOLOGY (2013)
von Economo neurones are selectively targeted in frontotemporal dementia
A. F. Santillo et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
Non-ATG-initiated translation directed by microsatellite expansions
Tao Zu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Effects of Gender in Amyotrophic Lateral Sclerosis
Pamela A. McCombe et al.
GENDER MEDICINE (2010)
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
Liqun Liu-Yesucevitz et al.
PLOS ONE (2010)
Gamma and alpha motor neurons distinguished by expression of transcription factor Err3
Andreas Friese et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The multifunctional nucleolus
Francois-Michel Boisvert et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Sexual dimorphism in disease onset and progression of a rat model of ALS
Masatoshi Suzuki et al.
AMYOTROPHIC LATERAL SCLEROSIS (2007)
The nucleolus: reviewing oldies to have new understandings
Szecheng J. Lo et al.
CELL RESEARCH (2006)
Share Paper
