Journal
JOURNAL OF CLINICAL MEDICINE
Volume 10, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/jcm10040683
Keywords
heparin-induced thrombocytopenia (HIT); new concepts; pathogenesis; diagnosis; management; immune PF4; heparin; antibody complexes; Bayesian diagnostic thinking; therapeutic plasma exchange; intravenous immunoglobulins (IVIG)
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Knowledge on heparin-induced thrombocytopenia is expanding with recent advancements in diagnosis, management, and discoveries on its pathogenesis. However, many aspects of the condition remain unclear, and further research is needed to fully understand and apply these new insights.
Knowledge on heparin-induced thrombocytopenia keeps increasing. Recent progress on diagnosis and management as well as several discoveries concerning its pathogenesis have been made. However, many aspects of heparin-induced thrombocytopenia remain partly unknown, and exact application of these new insights still need to be addressed. This article reviews the main new concepts in pathogenesis, diagnosis, and management of heparin-induced thrombocytopenia.
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