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T. Shishido et al.
NEUROLOGY (2010)
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Des R. Richardson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Binding and uptake of H-ferritin are mediated by human transferrin receptor-1
Li Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
α-Synuclein and dopamine at the crossroads of Parkinson's disease
Lara Lourenco Venda et al.
TRENDS IN NEUROSCIENCES (2010)
Generation and characterization of transgenic mice hyper-expressing melanoma tumour antigen p97 (Melanotransferrin): No overt alteration in phenotype
Yohan Suiyo Rahmanto et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Hepcidin, the hormone of iron metabolism, is bound specifically to α-2-macroglobulin in blood
Gabriela Peslova et al.
BLOOD (2009)
Role of iron in neurotoxicity: a cause for concern in the elderly?
James M. Stankiewicz et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2009)
Oligodendrocytes and Myelination: The Role of Iron
Bozho Todorich et al.
GLIA (2009)
Physiological and Pathological Role of Alpha-synuclein in Parkinson's Disease Through Iron Mediated Oxidative Stress; The Role of a Putative Iron-responsive Element
David Olivares et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)
Inhibition of Prolyl Hydroxylase Protects against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurotoxicity MODEL FOR THE POTENTIAL INVOLVEMENT OF THE HYPOXIA-INDUCIBLE FACTOR PATHWAY IN PARKINSON DISEASE
Donna W. Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1
Jeff Blackinton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain
Carol A. Colton
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2009)
Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
Wakoto Matsuda et al.
JOURNAL OF NEUROSCIENCE (2009)
α-Synuclein and neuronal cell death
Mark R. Cookson
MOLECULAR NEURODEGENERATION (2009)
Genome-wide association study reveals genetic risk underlying Parkinson's disease
Javier Simon-Sanchez et al.
NATURE GENETICS (2009)
Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in MES23.5 cells
Shuzhen Zhang et al.
NEUROBIOLOGY OF AGING (2009)
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease
Pier Giorgio Mastroberardino et al.
NEUROBIOLOGY OF DISEASE (2009)
Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity
Xiaomin Su et al.
NEUROTOXICITY RESEARCH (2009)
Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport
Ajay Singh et al.
PLOS ONE (2009)
Neuropathology of non-motor features of Parkinson disease
Dennis W. Dickson et al.
PARKINSONISM & RELATED DISORDERS (2009)
Dissecting the potential molecular mechanisms underlying a-synuclein cell-to-cell transfer in Parkinson's disease
Elodie Angot et al.
PARKINSONISM & RELATED DISORDERS (2009)
Non-motor extranigral signs and symptoms in Parkinson's disease
Erik Ch Wolters
PARKINSONISM & RELATED DISORDERS (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Repression of α-synuclein expression and toxicity by microRNA-7
Eunsung Junn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
Michael Li-Hsuan Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Is Parkinson's disease a prion disorder?
C. Warren Olanow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
Ajay A. Vashisht et al.
SCIENCE (2009)
α-Synuclein and Polyunsaturated Fatty Acids Promote Clathrin-Mediated Endocytosis and Synaptic Vesicle Recycling
Tziona Ben Gedalya et al.
TRAFFIC (2009)
Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2
Natalie J. Foot et al.
BLOOD (2008)
The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease
Tianhong Pan et al.
BRAIN (2008)
Oxidative stress and neurotoxicity
Lawrence M. Sayre et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Metal Catalyzed Oxidation of Alpha-Synuclein - A Role for Oligomerization in Pathology?
N. B. Cole
CURRENT ALZHEIMER RESEARCH (2008)
Genetic variability in the SNCA gene influences α-synuclein levels in the blood and brain
Julia Fuchs et al.
FASEB JOURNAL (2008)
MRI Assessment of Basal Ganglia Iron Deposition in Parkinson's Disease
Lauren I. Wallis et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2008)
Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease
David Sulzer et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Tim-2 is the receptor for H-ferritin on oligodendrocytes
Bozho Todorich et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Lewy body pathology involves cutaneous nerves
Masako Ikemura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Dopamine D2 Receptor Expression Is Altered by Changes in Cellular Iron Levels in PC12 Cells and Rat Brain Tissue
Erica L. Unger et al.
JOURNAL OF NUTRITION (2008)
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
Anthony H. V. Schapira
LANCET NEUROLOGY (2008)
Silencing α-synuclein gene expression enhances tyrosine hydroxylase activity in MN9D cells
Dongmei Liu et al.
NEUROCHEMICAL RESEARCH (2008)
α-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity:: Lessons from viral transduction of knockout mice
Tshianda N. M. Alerte et al.
NEUROSCIENCE LETTERS (2008)
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation
Megan Whitnall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals
Luigi Zecca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways
Marcel P. van der Brug et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
Julio Salazar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A cytosolic iron chaperone that delivers iron to ferritin
Haifeng Shi et al.
SCIENCE (2008)
Iron trafficking inside the brain
Torben Moos et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Mitochondrial ferritin expression in adult mouse tissues
Paolo Santambrogio et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
The pivotal role of astrocytes in the metabolism of iron in the brain
Ralf Dringen et al.
NEUROCHEMICAL RESEARCH (2007)
Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo
Y. Suryo Rahmanto et al.
CARCINOGENESIS (2007)
Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures
Julie A. Gaasch et al.
NEUROCHEMICAL RESEARCH (2007)
The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark - from iron metabolism to tumorigenesis
Y. Suryo Rahmanto et al.
ONCOGENE (2007)
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
Eva Andres-Mateos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activity
Paul V. Bernhardt et al.
DALTON TRANSACTIONS (2007)
Thermodynamics imprinting reveals differential binding of metals to α-synuclein:: Relevance to parkinson's disease
Bharathi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Iron chelation and regulation of the cell cycle:: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion
Dong Fu et al.
BLOOD (2007)
Selective iron chelation in Friedreich ataxia:: biologic and clinical implications
Nathalie Boddaert et al.
BLOOD (2007)
Direct interorganellar transfer of iron from endosome to mitochondrion
Alex D. Sheftel et al.
BLOOD (2007)
CD163-expressing monocytes constitute an endotoxinsensitive Hb clearance compartment within the vascular system
Christian A. Schaer et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells
J. Erin Tillman et al.
CANCER RESEARCH (2007)
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
Celine Perier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
Mayka Sanchez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Space, time and dopamine
Gordon W. Arbuthnott et al.
TRENDS IN NEUROSCIENCES (2007)
Iron uptake and metabolism in the new millennium
Louise L. Dunn et al.
TRENDS IN CELL BIOLOGY (2007)
Mechanistic aspects of Parkinson's disease:: α-synuclein and the biomembrane
Klaus Beyer
CELL BIOCHEMISTRY AND BIOPHYSICS (2007)
Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators
Wen Zhu et al.
FASEB JOURNAL (2007)
The 5 '-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element
A. L. Friedlich et al.
MOLECULAR PSYCHIATRY (2007)
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels
Gyorgy Szabadkai et al.
JOURNAL OF CELL BIOLOGY (2006)
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
Andong Qiu et al.
CELL (2006)
The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis
L. L. Dunn et al.
CARCINOGENESIS (2006)
Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin
Christian A. Schaer et al.
CIRCULATION RESEARCH (2006)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
The roles of intracellular protein-degradation pathways in neurodegeneration
David C. Rubinsztein
NATURE (2006)
Mechanisms of Parkinson's disease linked to pathological α-synuclein:: New targets for drug discovery
Virginia M. -Y. Lee et al.
NEURON (2006)
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
Megan Whitnall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease
Demetrius M. Maraganore et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Neuromelanin and iron in human locus coeruleus and substantia nigra during aging: consequences for neuronal vulnerability
F. A. Zucca et al.
JOURNAL OF NEURAL TRANSMISSION (2006)
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
Beisha Tang et al.
HUMAN MOLECULAR GENETICS (2006)
Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multildrug resistance-associated protein 1
Ralph N. Watts et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
Paula M. Keeney et al.
JOURNAL OF NEUROSCIENCE (2006)
Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid
LK Charkoudian et al.
INORGANIC CHEMISTRY (2006)
Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo
EO Sekyere et al.
BLOOD (2006)
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
DJ Schaer et al.
BLOOD (2006)
Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
NATURE REVIEWS NEUROSCIENCE (2006)
The evolution of iron chelators for the treatment of iron overload disease and cancer
DS Kalinowski et al.
PHARMACOLOGICAL REVIEWS (2005)
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction
J Park et al.
GENE (2005)
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
AB West et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
RS Ohgami et al.
NATURE GENETICS (2005)
In vivo detection of iron and neuromelanin by transcranial sonography: A new of substantia approach for early detection nigra damage
L Zecca et al.
MOVEMENT DISORDERS (2005)
Identification of an intestinal heme transporter
M Shayeghi et al.
CELL (2005)
α-Synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells
XMM Peng et al.
JOURNAL OF CELL SCIENCE (2005)
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
L Zhang et al.
HUMAN MOLECULAR GENETICS (2005)
Skin and platelet α-synuclein as peripheral biomarkers of Parkinson's disease
AW Michell et al.
NEUROSCIENCE LETTERS (2005)
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
RH Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization
J Blackinton et al.
MOLECULAR BRAIN RESEARCH (2005)
Structural characterization of copper(II) binding to α-synuclein:: Insights into the bioinorganic chemistry of Parkinson's disease
RM Rasia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features
RL Sham et al.
BLOOD CELLS MOLECULES AND DISEASES (2005)
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis
GJ Nie et al.
BLOOD (2005)
Iron trafficking in the mitochondrion: novel pathways revealed by disease
I Napier et al.
BLOOD (2005)
Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease
M Hsu et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
MS Goldberg et al.
NEURON (2005)
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria
AS Zhang et al.
BLOOD (2005)
Environmental toxins and alpha-synuclein in Parkinson's disease
YY Liu et al.
MOLECULAR NEUROBIOLOGY (2005)
Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease
H Fedorow et al.
PROGRESS IN NEUROBIOLOGY (2005)
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
DJ Moore et al.
HUMAN MOLECULAR GENETICS (2005)
α-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells -: Intermediacy of transferrin receptor iron and hydrogen peroxide
SV Kalivendi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Autosomal dominant iron overload due to a novel mutation of ferroportin1 associated with parenchymal iron loading and cirrhosis
DF Wallace et al.
JOURNAL OF HEPATOLOGY (2004)
Mossbauer spectroscopy and ELISA studies reveal differences between. Parkinson's disease and control substantia nigra
J Galazka-Friedman et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2004)
Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study
H Watanabe et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2004)
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function
JA Olzmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
DJ-1 has a role in antioxidative stress to prevent cell death
T Taira et al.
EMBO REPORTS (2004)
Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats
D Ben Shachar et al.
NEUROPHARMACOLOGY (2004)
Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment
J Yuan et al.
BLOOD (2004)
Inhibition of tyrosine hydroxylase expression in α-synuclein-transfected dopaminergic neuronal cells
S Yu et al.
NEUROSCIENCE LETTERS (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
The neuromelanin of human substantia nigra: Physiological and pathogenic aspects
FA Zucca et al.
PIGMENT CELL RESEARCH (2004)
Molecular pathways to neurodegeneration
E Bossy-Wetzel et al.
NATURE MEDICINE (2004)
Hereditary haemochromatosis is unlikely to cause movement disorders - A critical review
N Russo et al.
JOURNAL OF NEUROLOGY (2004)
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
L Zecca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain
T Moos et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Could a loss of α-synuclein function put dopaminergic neurons at risk?
RG Perez et al.
JOURNAL OF NEUROCHEMISTRY (2004)
The transferrin homologue, melan transferrin (p97), is rapidly catabolized by the liver of the rat anal does not effectively donate iron to the brain
DR Richardson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2004)
Stages in the development of Parkinson's disease-related pathology
H Braak et al.
CELL AND TISSUE RESEARCH (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells
T Kinumi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism
V Bonifati et al.
NEUROLOGICAL SCIENCES (2003)
The effect of potent iron chelators on the regulation of p53:: examination of the expression, localization and DNA-binding activity of p53 and the transactivation of WAF1
SX Liang et al.
CARCINOGENESIS (2003)
Expression of melanotransferrin isoforms in human serum:: relevance to Alzheimer's disease
RR Desrosiers et al.
BIOCHEMICAL JOURNAL (2003)
The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?
DA Di Monte
LANCET NEUROLOGY (2003)
The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
MA Wilson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
SY Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Myelination and motor coordination are increased in transferrin transgenic mice
MC Saleh et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2003)
Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1, but paradoxically inhibit its translation:: a potential mechanism of cell cycle dysregulation
NTV Le et al.
CARCINOGENESIS (2003)
Residual substantia nigra neuromelanin in Parkinson's disease is cross-linked to α-synuclein
M Fasano et al.
NEUROCHEMISTRY INTERNATIONAL (2003)
Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells
G Link et al.
BLOOD (2003)
Co-ordinate transcriptional regulation of dopamine synthesis genes by α-synuclein in human neuroblastoma cell lines
MJ Baptista et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Neonatal iron deficiency results in irreversible changes in dopamine function in rats
J Beard et al.
JOURNAL OF NUTRITION (2003)
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation:: role of transferrin-receptor-dependent iron and hydrogen peroxide
SV Kalivendi et al.
BIOCHEMICAL JOURNAL (2003)
Aceruloplasminemia, an inherited disorder of iron metabolism
H Miyajima et al.
BIOMETALS (2003)
Lipid interaction of α-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2
EN Lee et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia
M Cazzola et al.
BLOOD (2003)
Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron
RN Watts et al.
BIOCHEMICAL JOURNAL (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
Neuropathological spectrum of synucleinopathies
KA Jellinger
MOVEMENT DISORDERS (2003)
Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein
J Lotharius et al.
NATURE REVIEWS NEUROSCIENCE (2002)
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
N Hubert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Nonselenium glutathione peroxidase in human brain - Elevated levels in Parkinson's disease and dementia with Lewy bodies
JHT Power et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice
FS Canonne-Hergaux et al.
KIDNEY INTERNATIONAL (2002)
The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells - NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner
RN Watts et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice
M Okada et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2002)
Dopamine-dependent neurotoxicity of α-synuclein:: A mechanism for selective neurodegeneration in Parkinson disease
J Xu et al.
NATURE MEDICINE (2002)
A role for α-synuclein in the regulation of dopamine biosynthesis
RG Perez et al.
JOURNAL OF NEUROSCIENCE (2002)
The iron metabolism of neoplastic cells: alterations that facilitate proliferation?
JC Kwok et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2002)
Human α-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine
E Junn et al.
NEUROSCIENCE LETTERS (2002)
The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease
L Zecca et al.
FEBS LETTERS (2002)
Iron-dependent regulation of the divalent metal ion transporter
H Gunshin et al.
FEBS LETTERS (2001)
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASxα to the receptor
K Takahashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: the mechanisms involved in inhibiting cell-cycle progression
J Gao et al.
BLOOD (2001)
Iron and iron management proteins in neurobiology
JR Connor et al.
PEDIATRIC NEUROLOGY (2001)
A human mitochondrial ferritin encoded by an intronless gene
S Levi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Parkinson's disease and related neurodegenerative synucleinopathies linked to progressive accumulations of synuclein aggregates in brain
JQ Trojanowski et al.
PARKINSONISM & RELATED DISORDERS (2001)
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
OT Njajou et al.
NATURE GENETICS (2001)
Serum melanotransferrin, p97 as a biochemical marker of Alzheimer's disease
DK Kim et al.
NEUROPSYCHOPHARMACOLOGY (2001)
Iron deficiency decreases dopamine D1 and D2 receptors in rat brain
KM Erikson et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2001)
Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron
DR Richardson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2001)
The controversial role of deferiprone in the treatment of thalassemia
DR Richardson
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2001)
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
C Pigeon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
An iron-regulated ferric reductase associated with the absorption of dietary iron
AT McKie et al.
SCIENCE (2001)
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