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NEW ENGLAND JOURNAL OF MEDICINE (2010)
Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion
Toshyuki Nakayama et al.
ONCOLOGY REPORTS (2010)
Serum fetuin A/α2HS-glycoprotein levels in patients with non-alcoholic fatty liver disease: relation with liver fibrosis
Yusuf Yilmaz et al.
ANNALS OF CLINICAL BIOCHEMISTRY (2010)
A Complex Role of Activin A in Non-Alcoholic Fatty Liver Disease
Arne Yndestad et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2009)
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models-association with liver and adipose tissue effects
Jing Xu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids
Sander Kersten et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity
M. Mraz et al.
CLINICAL ENDOCRINOLOGY (2009)
Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
Jing Xu et al.
DIABETES (2009)
Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance
Alberto O. Chavez et al.
DIABETES CARE (2009)
Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver
Yuhei Hotta et al.
ENDOCRINOLOGY (2009)
Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance
Yusuf Yimaz et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2009)
FGF21 N- and C-termini play different roles in receptor interaction and activation
Junming Yie et al.
FEBS LETTERS (2009)
High Glucose Induces Transactivation of the alpha 2-HS Glycoprotein Gene Through the ERK1/2 Signaling Pathway
Hiroshi Takata et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2009)
Major Urinary Protein-1 Increases Energy Expenditure and Improves Glucose Intolerance through Enhancing Mitochondrial Function in Skeletal Muscle of Diabetic Mice
Xiaoyan Hui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Different Roles of N- and C-Termini in the Functional Activity of FGF21
Radmila Micanovic et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
INHIBITION OF MYOSTATIN WITH EMPHASIS ON FOLLISTATIN AS A THERAPY FOR MUSCLE DISEASE
Louise R. Rodino-Klapac et al.
MUSCLE & NERVE (2009)
Serum levels of angiopoietin-related growth factor in diabetes mellitus and chronic hemodialysis
Thomas Ebert et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2009)
Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects
E. Succurro et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2009)
FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
Matthew J. Potthoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Plasma fetuin-A levels and the risk of type 2 diabetes
Norbert Stefan et al.
DIABETES (2008)
Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
Xinmei Zhang et al.
DIABETES (2008)
Fibroblast Growth Factor 21 Corrects Obesity in Mice
Tamer Coskun et al.
ENDOCRINOLOGY (2008)
Fetuin-A and Its Relation to Metabolic Syndrome and Fatty Liver Disease in Obese Children Before and After Weight Loss
Thomas Reinehr et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
βKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
Masashi Suzuki et al.
MOLECULAR ENDOCRINOLOGY (2008)
Fetuin-A Induces Cytokine Expression and Suppresses Adiponectin Production
Anita M. Hennige et al.
PLOS ONE (2008)
The role of angiopoictin-like proteins in angiogenesis and metabolism
Tai Hato et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2008)
Circulating FGF-21 levels in normal subjects and in newly diagnose patients with type 2 diabetes Mellitus
W. -W. Chen et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2008)
Angiopoietin-related growth factor suppresses gluconeogenesis through the akt/forkhead box class O1-Dependent pathway in Hepatocytes
Masashi Kitazawa et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-Dependent hepatic cholesterol uptake
Laeticia Lichtenstein et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
Heiko Johnen et al.
NATURE MEDICINE (2007)
Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor Isoforms determines metabolic activity of FGF19 and FGF21
Hiroshi Kurosu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice
Urvi Desai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states
Michael K. Badman et al.
CELL METABOLISM (2007)
Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21
Takeshi Inagaki et al.
CELL METABOLISM (2007)
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL
Stefano Romeo et al.
NATURE GENETICS (2007)
Inflammation and metabolic disorders
Goekhan S. Hotamisligil
NATURE (2006)
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue
Valentina Sukonina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia
Seung Joon Baek et al.
GASTROENTEROLOGY (2006)
Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR
Kimihiko Matsusue et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2006)
Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin, and bone morphogenetic proteins
Yisrael Sidis et al.
ENDOCRINOLOGY (2006)
Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
Asne R. Bauskin et al.
CANCER RESEARCH (2006)
The lipoprotein lipase inhibitor ANGPTL3 is negatively regulated by thyroid hormone
C Fugier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity
S Mandard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Lipocalins - a family portrait
Joanna Grzyb et al.
JOURNAL OF PLANT PHYSIOLOGY (2006)
Transgenic angiopoietin-like (Angptl)4 overexpression and targeted disruption of Angptl4 and Angptl3:: Regulation of triglyceride metabolism
A Köster et al.
ENDOCRINOLOGY (2005)
FGF-21 as a novel metabolic regulator
A Kharitonenkov et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
AM Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Angiopoietin-related growth factor antagonizes obesity and insulin resistance
Y Oike et al.
NATURE MEDICINE (2005)
A brain-liver circuit regulates glucose homeostasis
A Pocai et al.
CELL METABOLISM (2005)
Specific roles for the PI3K and the MEK-ERK pathway in IGF-1-stimulated chemotaxis, VEGF secretion and proliferation of multiple myeloma cells: study in the 5T33MM model
E Menu et al.
BRITISH JOURNAL OF CANCER (2004)
Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor
M Shimamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes
M Krssak et al.
DIABETES (2004)
Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of β-catenin in the liver
C Ovejero et al.
HEPATOLOGY (2004)
Angiopoietin-related/angiopoietin-like proteins regulate angiogenesis
Y Oike et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2004)
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states
K Inukai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Differential distribution of follistatin isoforms: Application of a new FS315-specific immunoassay
AL Schneyer et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3) -: ANGPTL3 is cleaved and activated in vivo
M Ono et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hepatic glucose metabolism in humans - its role in health and disease
M Roden et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Overexpression of activin βC or activin βE in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells
M Chabicovsky et al.
ENDOCRINOLOGY (2003)
Inhibins, activins and follistatin in reproduction
DM de Kretser et al.
HUMAN REPRODUCTION UPDATE (2002)
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase
T Shimizugawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
cDNA cloning and expression of human activin βE subunit
O Hashimoto et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)
Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease - A population-based case-control study
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CIRCULATION (2002)
Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene
ST Mathews et al.
DIABETES (2002)
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study
MS Sandhu et al.
LANCET (2002)
Functional inactivation, of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
AM Fernández et al.
GENES & DEVELOPMENT (2001)
Possible changes in expression of chemotaxin LECT2 mRNA in mouse liver after concanavalin A-induced hepatic injury
Y Segawa et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2001)
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
S Kersten et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Placental transforming growth factor-β is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression
PX Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
T Nishimura et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
α2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor
ST Mathews et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2000)
Characterization of growth-differentiation factor 15, a transforming growth factor β superfamily member induced following liver injury
EC Hsiao et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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