Journal
FRONTIERS IN IMMUNOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2021.621311
Keywords
extracellular DNA traps; evolution; multicellular organisms; extracellular neutrophil traps; neutrophils
Categories
Funding
- National Technology of Mexico/IT Oaxaca [8703.20-P]
- Benito Juarez Autonomous University of Oaxaca
- Direccion General de Asuntos del Personal Academico (DGAPA National Autonomous University of Mexico), UNAM [PAPIIT-IN201019]
Ask authors/readers for more resources
Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms found in protozoa, plants, and animals. By comparing similarities in ETs across different taxa, it is suggested that ETs may have multiple origins. The presence of a mechanism initiating the formation of ETs in multicellular organisms indicates a relationship between multicellularity and the development of ETs.
Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have multiple origins. Our results are consistent with a process of evolutionary convergence in multicellular organisms through the application of a congruency test. Furthermore, we discuss why multicellularity is related to the presence of a mechanism initiating the formation of ETs.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available