4.8 Review

3D Tissue and Organ Printing-Hope and Reality

Journal

ADVANCED SCIENCE
Volume 8, Issue 10, Pages -

Publisher

WILEY
DOI: 10.1002/advs.202003751

Keywords

3D printing; bioinks; biomaterials; cells; tissue engineering

Funding

  1. European Research Council (ERC) [637943]
  2. Slezak Foundation

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3D bioprinting is an emerging technology with great potential in tissue engineering. Despite challenges, innovative approaches and advanced technologies can address current issues and pave the way for future directions.
Three-dimensional (3D) bioprinting is an emerging, groundbreaking strategy in tissue engineering, allowing the fabrication of living constructs with an unprecedented degree of complexity and accuracy. While this technique greatly facilitates the structuring of native tissue-like architectures, many challenges still remain to be faced. In this review, the fruits of recent research that demonstrate how advanced bioprinting technologies, together with inspiring creativity, can be used to address these challenges are presented and discussed. Next, the future of the field is discussed, in terms of expected developments, as well as possible directions toward the realization of the vision of fully functional, engineered tissues, and organs. Last, a few hypothetical scenarios for the role 3D bioprinting may play in future tissue engineering are depicted, with an emphasis on its impact on tomorrow's regenerative medicine.

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