Journal
FRONTIERS IN PHARMACOLOGY
Volume 11, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2020.552453
Keywords
snowdrop; galanthus; bioactivities; galanthamine; lycorine
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Funding
- Monash Global Asia in the 21st Centrury (GA21) [GA-HW-19-L01, GAHW-19-S02]
- Fundamental Research Grant Scheme [FRGS/1/2019/WAB09/MUSM/02/1, FRGS/1/2019/SKK08/TAYLOR/02/02]
- Taylor's University Emerging Grant [TRGS/ERFS/2/2018/SBS/016]
- External Industry Grant from Biotek Abadi Sdn Bhd [GBA-8188A]
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Snowdrop, an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae), is economically important as an ornament and has gained scientific and commercial interest due to the discovery of Galanthamine as a treatment for Alzheimer's disease. This review discusses the bioactivities of Galanthus spp including anticholinesterase, antimicrobial, antioxidant, and anticancer potential, highlighting their potential for drug discovery and nutraceutical development.
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae). Galanthus species (Galanthus spp.) are economically important plants as ornaments. Galanthus spp has gained significance scientific and commercial interest due to the discovery of Galanthamine as symptomatic treatment drug for Alzhiermer disease. This review aims to discuss the bioactivities of Galanthus spp including anticholinesterase, antimicrobial, antioxidant and anticancer potential of the extracts and chemical constituents of Galanthus spp. This review highlights that Galanthus spp. as the exciting sources for drug discovery and nutraceutical development.
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