Journal
FRONTIERS IN PHARMACOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2021.627574
Keywords
drug repurposing; drug licensing; antineoplastic drugs; licensed drugs; database; list of cancer drugs
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Currently, there is no global, unified listing of approved anticancer drugs, but a methodology exists to combine and cleanse relevant data from multiple sources to produce a database specifically for therapeutic antineoplastic purposes, which can be used by researchers as input for further research projects.
A global, comprehensive and open access listing of approved anticancer drugs does not currently exist. Partial information is available from multiple sources, including regulatory authorities, national formularies and scientific agencies. Many such data sources include drugs used in oncology for supportive care, diagnostic or other non-antineoplastic uses. We describe a methodology to combine and cleanse relevant data from multiple sources to produce an open access database of drugs licensed specifically for therapeutic antineoplastic purposes. The resulting list is provided as an open access database, (http://www.redo-project.org/cancer-drugs-db/), so that it may be used by researchers as input for further research projects, for example literature-based text mining for drug repurposing.
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