☆ 4.4 Letter

Persistence of Δ-9-Tetrahydrocannabinol in Human Breast Milk

JAMA PEDIATRICS (2021)

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Article Chemistry, Analytical

Detection of Cannabinoids by LC-MS-MS and ELISA in Breast Milk

Cristina Sempio et al.

Summary: This study validated a sensitive and specific high-performance liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of 12 cannabinoids in human breastmilk, outperforming the commonly used enzyme-linked immunosorbent assay (ELISA) in breastmilk banks. The assay demonstrated successful quantification of cannabinoids and their metabolites in breastmilk samples that tested negative using ELISA, highlighting the importance of using LC-MS-MS for clinical monitoring and research studies in this area.

JOURNAL OF ANALYTICAL TOXICOLOGY (2021)

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Article Obstetrics & Gynecology