4.6 Article

Automatic Construction of Chinese Herbal Prescriptions From Tongue Images Using CNNs and Auxiliary Latent Therapy Topics

Journal

IEEE TRANSACTIONS ON CYBERNETICS
Volume 51, Issue 2, Pages 708-721

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TCYB.2019.2909925

Keywords

Convolution channels; neural networks; prescriptions construction; therapy topics; tongue images

Funding

  1. Guangdong Province Higher Vocational Colleges and Schools Pearl River Scholar Funded Scheme [2018]
  2. National Natural Science Foundation of China [60973083, 61273363, 61722205, 61751205, 61751202, 61572199, 61502174, U1611461]
  3. Science and Technology Planning Projects of Guangdong Province [2014A010103009, 2015A020217002, 2018B010107002]
  4. Guangzhou Science and Technology Planning Project [201504291154480]

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The tongue image provides important physical information and the technology for constructing herbal prescriptions based on it can be widely applied in mobile medical systems. The research proposes a neural network framework that can generate prescriptions close to real samples, providing a new approach for automatic herbal prescription construction.
The tongue image provides important physical information of humans. It is of great importance for diagnoses and treatments in clinical medicine. Herbal prescriptions are simple, noninvasive, and have low side effects. Thus, they are widely applied in China. Studies on the automatic construction technology of herbal prescriptions based on tongue images have great significance for deep learning to explore the relevance of tongue images for herbal prescriptions, it can be applied to healthcare services in mobile medical systems. In order to adapt to the tongue image in a variety of photographic environments and construct herbal prescriptions, a neural network framework for prescription construction is designed. It includes single/double convolution channels and fully connected layers. Furthermore, it proposes the auxiliary therapy topic loss mechanism to model the therapy of Chinese doctors and alleviate the interference of sparse output labels on the diversity of results. The experiment use the real-world tongue images and the corresponding prescriptions and the results can generate prescriptions that are close to the real samples, which verifies the feasibility of the proposed method for the automatic construction of herbal prescriptions from tongue images. Also, it provides a reference for automatic herbal prescription construction from more physical information.

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