Related references
Note: Only part of the references are listed.Taking the Occam's Razor Approach to Hedgehog Lipidation and Its Role in Development
Dominique Manikowski et al.
JOURNAL OF DEVELOPMENTAL BIOLOGY (2018)
Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated release
Petra Jakobs et al.
JOURNAL OF CELL SCIENCE (2017)
Bridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells
P. Jakobs et al.
SCIENTIFIC REPORTS (2016)
Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans
Corinna Ortmann et al.
JOURNAL OF CELL SCIENCE (2015)
Sonic hedgehog multimerization: A self-organizing event driven by post-translational modifications?
Mirella V. Koleva et al.
MOLECULAR MEMBRANE BIOLOGY (2015)
Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms
Michael Cohen et al.
NATURE COMMUNICATIONS (2015)
Mathematical Modelling of Digit Specification by a Sonic Hedgehog Gradient
Thomas E. Woolley et al.
DEVELOPMENTAL DYNAMICS (2014)
Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties
Neha Vyas et al.
SCIENTIFIC REPORTS (2014)
Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning
Alexander M. Holtz et al.
DEVELOPMENT (2013)
Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning
Timothy A. Sanders et al.
NATURE (2013)
Morphogenetic action through flux-limited spreading
M. Verbeni et al.
PHYSICS OF LIFE REVIEWS (2013)
Structural insights into proteoglycan-shaped Hedgehog signaling
Daniel M. Whalen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Computational microscopy of cyclodextrin mediated cholesterol extraction from lipid model membranes
Cesar A. Lopez et al.
SCIENTIFIC REPORTS (2013)
Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals
Wilhelm Palm et al.
PLOS BIOLOGY (2013)
Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube
Nikolaos Balaskas et al.
CELL (2012)
Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form
Adrian Creanga et al.
GENES & DEVELOPMENT (2012)
Dispatched and Scube Mediate the Efficient Secretion of the Cholesterol-Modified Hedgehog Ligand
Hanna Tukachinsky et al.
CELL REPORTS (2012)
Sonic Hedgehog Shedding Results in Functional Activation of the Solubilized Protein
Stefanie Ohlig et al.
DEVELOPMENTAL CELL (2011)
Two Distinct Sites in Sonic Hedgehog Combine for Heparan Sulfate Interactions and Cell Signaling Functions
Shu-Chun Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Lipid Modifications of Sonic Hedgehog Ligand Dictate Cellular Reception and Signal Response
Vandana K. Grover et al.
PLOS ONE (2011)
Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction
Cesar A. Lopez et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Robustness of positional specification by the Hedgehog morphogen gradient
David J. Irons et al.
DEVELOPMENTAL BIOLOGY (2010)
Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog
Eric Dessaud et al.
PLOS BIOLOGY (2010)
Molecular View of Cholesterol Flip-Flop and Chemical Potential in Different Membrane Environments
W. F. Drew Bennett et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Dynamic Interpretation of Hedgehog Signaling in the Drosophila Wing Disc
Marcos Nahmad et al.
PLOS BIOLOGY (2009)
Nanoscale organization of Hedgehog is essential for long-range signaling
Neha Vyas et al.
CELL (2008)
Patched, the receptor of Hedgehog, is a lipoprotein receptor
Ainhoa Callejo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hedgehog signaling is essential for normal wound healing
Huong Le et al.
WOUND REPAIR AND REGENERATION (2008)
Lipoprotein-heparan sulfate interactions in the Hh pathway
Christina Eugster et al.
DEVELOPMENTAL CELL (2007)
Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord
Xi Huang et al.
DEVELOPMENT (2007)
Cholesterol modification restricts the spread of Shh gradient in the limb bud
YN Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Signal dynamics in Sonic hedgehog tissue patterning
K Saha et al.
DEVELOPMENT (2006)
A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form
JA Goetz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia
A Gallet et al.
DEVELOPMENT (2006)
Heparan sulfate proteoglycans exert positive and negative effects in Shh activity
H Carrasco et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Lipoprotein particles are required for Hedgehog and Wingless signalling
D Panáková et al.
NATURE (2005)
The Sonic hedgehog signaling system as a bistable genetic switch
K Lai et al.
BIOPHYSICAL JOURNAL (2004)
Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation
C Han et al.
DEVELOPMENT (2004)
Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates
MH Chen et al.
GENES & DEVELOPMENT (2004)
Synergistic and antagonistic roles of the Sonic hedgehog N- and C-terminal lipids
J Feng et al.
DEVELOPMENT (2004)
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans
Y Takei et al.
DEVELOPMENT (2004)
The Hedgehog response network: Sensors, switches, and routers
L Lum et al.
SCIENCE (2004)
The cholesterol membrane anchor of the hedgehog protein confers stable membrane association to lipid-modified proteins
C Peters et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Stationary Kolmogorov solutions of the Smoluchowski aggregation equation with a source term
C Connaughton et al.
PHYSICAL REVIEW E (2004)
Short- and long-range effects of Sonic hedgehog in limb development
R Dillon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of Sonic hedgehog in the neural tube
J Briscoe et al.
MOLECULAR CELL (2001)
A freely diffusible form of Sonic hedgehog mediates long-range signalling
X Zeng et al.
NATURE (2001)
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1
PM Lewis et al.
CELL (2001)
Share Paper
