4.6 Article

Effectiveness of interventions to reduce COVID-19 transmission in a large urban jail: a model-based analysis

Journal

BMJ OPEN
Volume 11, Issue 2, Pages -

Publisher

BMJ PUBLISHING GROUP
DOI: 10.1136/bmjopen-2020-042898

Keywords

COVID-19; epidemiology; health policy; public health; infection control

Funding

  1. Agency for Healthcare Research and Quality [T32HS026128]
  2. National Institute on Drug Abuse [R37-DA15612]
  3. Veterans Health Administration
  4. Yale University from the Bureau of Justice Administration [2015-RY-BX-K002]
  5. Substance Abuse and Mental Health Services Administration
  6. Yale University from the National Cancer Institute of National Institute of Health [1R01CA230444]
  7. National Heart, Lung and Blood Institute [1R01HL137696]
  8. National Institute of Minority Health and Disparities [1R01MD010403]
  9. National Institute of Drug Abuse [1UG1DA050072, 3 UG1 DA050072-02S3]
  10. National Library of Medicine [1 R01LM013477-01]
  11. William T Grant Foundation [188795]
  12. California Healthcare Foundation [19-0 02 900]
  13. National Institute on Drug [3 UG1 DA050072-02S3]

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By modeling, interventions such as depopulation, increasing the proportion of single cells, and testing asymptomatic individuals in jails were found to effectively mitigate COVID-19 transmission, preventing approximately 83% of projected cases, hospitalizations, and deaths over 83 days.
Objectives We aim to estimate the impact of various mitigation strategies on COVID-19 transmission in a US jail beyond those offered in national guidelines. Design We developed a stochastic dynamic transmission model of COVID-19. Setting One anonymous large urban US jail. Participants Several thousand staff and incarcerated individuals. Interventions There were four intervention phases during the outbreak: the start of the outbreak, depopulation of the jail, increased proportion of people in single cells and asymptomatic testing. These interventions were implemented incrementally and in concert with one another. Primary and secondary outcome measures The basic reproduction ratio, R-0, in each phase, as estimated using the next generation method. The fraction of new cases, hospitalisations and deaths averted by these interventions (along with the standard measures of sanitisation, masking and social distancing interventions). Results For the first outbreak phase, the estimated R-0 was 8.44 (95% credible interval (CrI): 5.00 to 13.10), and for the subsequent phases, R-0,R- phase 2=3.64 (95% CrI: 2.43 to 5.11), R-0,R- phase 3=1.72 (95% CrI: 1.40 to 2.12) and R-0,R- phase 4=0.58 (95% CrI: 0.43 to 0.75). In total, the jail's interventions prevented approximately 83% of projected cases, hospitalisations and deaths over 83 days. Conclusions Depopulation, single celling and asymptomatic testing within jails can be effective strategies to mitigate COVID-19 transmission in addition to standard public health measures. Decision makers should prioritise reductions in the jail population, single celling and testing asymptomatic populations as additional measures to manage COVID-19 within correctional settings.

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