4.7 Article

Computational learning of features for automated colonic polyp classification

Journal

SCIENTIFIC REPORTS
Volume 11, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41598-021-83788-8

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Funding

  1. Cancer Prevention and Research Institute of Texas [CPRIT RP170668]

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This paper presents a comprehensive analysis of critical features in assessing dysplasia in colonic polyps, using shape, texture, and color descriptors. The study includes feature extraction, statistical analysis, and classification with machine learning algorithms, demonstrating efficient designation and early detection. The proposed approach out-performs existing methods in colonic polyp identification, as demonstrated through comparison with deep learning models.
Shape, texture, and color are critical features for assessing the degree of dysplasia in colonic polyps. A comprehensive analysis of these features is presented in this paper. Shape features are extracted using generic Fourier descriptor. The nonsubsampled contourlet transform is used as texture and color feature descriptor, with different combinations of filters. Analysis of variance (ANOVA) is applied to measure statistical significance of the contribution of different descriptors between two colonic polyps: non-neoplastic and neoplastic. Final descriptors selected after ANOVA are optimized using the fuzzy entropy-based feature ranking algorithm. Finally, classification is performed using Least Square Support Vector Machine and Multi-layer Perceptron with five-fold cross-validation to avoid overfitting. Evaluation of our analytical approach using two datasets suggested that the feature descriptors could efficiently designate a colonic polyp, which subsequently can help the early detection of colorectal carcinoma. Based on the comparison with four deep learning models, we demonstrate that the proposed approach out-performs the existing feature-based methods of colonic polyp identification.

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