4.7 Review

In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?

Journal

NUTRIENTS
Volume 13, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/nu13030870

Keywords

anti-viral; infant nutrition; lactoferrin; milk fat globule membrane; osteopontin; glycerol monolaurate; human milk oligosaccharides; probiotics; postbiotics; polyunsaturated fatty acids

Funding

  1. Reckitt Benckiser/Mead Johnson Nutrition

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The review summarizes components from human milk and infant nutrition that can support immunity against viral infections, such as lactoferrin and probiotics. These ingredients are beneficial for both children and adults, highlighting opportunities for further research in providing tangible nutrition solutions to enhance the immune system and combat infections.
In 2020, with the advent of a pandemic touching all aspects of global life, there is a renewed interest in nutrition solutions to support the immune system. Infants are vulnerable to infection and breastfeeding has been demonstrated to provide protection. As such, human milk is a great model for sources of functional nutrition ingredients, which may play direct roles in protection against viral diseases. This review aims to summarize the literature around human milk (lactoferrin, milk fat globule membrane, osteopontin, glycerol monolaurate and human milk oligosaccharides) and infant nutrition (polyunsaturated fatty acids, probiotics and postbiotics) inspired ingredients for support against viral infections and the immune system more broadly. We believe that the application of these ingredients can span across all life stages and thus apply to both pediatric and adult nutrition. We highlight the opportunities for further research in this field to help provide tangible nutrition solutions to support one's immune system and fight against infections.

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