Journal
MATERIALS
Volume 14, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/ma14040706
Keywords
magnetic hyperthermia; magnetic nanoparticles; hysteresis losses; cancer; magnetic particle imaging; theranostics; nanoparticles synthesis; thermometry; standardization; nanotoxicity
Categories
Funding
- NoCanTher project from the European Union's Horizon 2020 research and innovation program [685795]
- COST Association through the COST action RADIOMAG [TD1402]
- COST Association through the COST action MyWAVE [CA17115]
- Community of Madrid [PEJD-2017-PRE/IND-3663, PEJ-2018-AI/IND-11069]
- Spanish Ministry of Science through the Ramon y Cajal [RYC2018-025253-I]
- Ministry of Economy and Competitiveness [MAT2017-85617-R, MAT2017-88148R]
- Severo Ochoa Program for Centers of Excellence in RD [SEV-2016-0686]
- EPSRC [EP/K038656/1, EP/M015157/1]
- AOARD [FA2386-171-4042]
- EMPIR program
- European Union's Horizon 2020 research and innovation program [16NRM04]
- DFG grant CRC Matrix in Vision [SFB 1340/1 2018, 372486779]
- [RED2018-102626-T]
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The scientific community has put great efforts in advancing magnetic hyperthermia in the past two decades, with fruitful international cooperation and careful analysis of lessons learned providing better guarantees for the future development of this nanotherapy against cancer.
The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.
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