Related references
Note: Only part of the references are listed.Semi-rational engineering of a Kluyveromyces lactis aldo-keto reductase KlAKR for improved catalytic efficiency towards t-butyl 6-cyano-(3R, 5R)-dihydroxyhexanoate
Wei Shen et al.
ENZYME AND MICROBIAL TECHNOLOGY (2020)
Rational Design of Dehydrogenase/Reductases Based on Comparative Structural Analysis of Prereaction-State and Free-State Simulations for Efficient Asymmetric Reduction of Bulky Aryl Ketones
Bing-Mei Su et al.
ACS CATALYSIS (2020)
Structural insights into alcohol dehydrogenases catalyzing asymmetric reductions
Jianhong An et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2019)
Conformational Dynamics-Guided Loop Engineering of an Alcohol Dehydrogenase: Capture, Turnover and Enantioselective Transformation of Difficult-to-Reduce Ketones
Beibei Liu et al.
ADVANCED SYNTHESIS & CATALYSIS (2019)
Improving the catalytic efficiency of aldo-keto reductase KmAKR towards t-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate via semi-rational design
Han Yu et al.
BIOORGANIC CHEMISTRY (2019)
Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain
Afifa Ayu Koesoema et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)
Reversible control of enantioselectivity by the length of ketone substituent in biocatalytic reduction
Afifa Ayu Koesoema et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)
Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase
Xi Chen et al.
NATURE CATALYSIS (2019)
Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor
Xu-Min Gong et al.
ACS CATALYSIS (2019)
The biosynthetic origin of psychoactive kavalactones in kava
Tomas Pluskal et al.
NATURE PLANTS (2019)
Loop engineering reveals the importance of active-site-decorating loops and gating residue in substrate affinity modulation of arginine deiminase (an anti-tumor enzyme)
Feng Cheng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Introduction: Biocatalysis in Industry
Greg Hughes et al.
CHEMICAL REVIEWS (2018)
Discovery of a Switch Between Prelog and Anti-Prelog Reduction toward Halogen-Substituted Acetophenones in Short-Chain Dehydrogenase/Reductases
Fengyu Qin et al.
ACS CATALYSIS (2018)
Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a Polar Gate in Stereorecognition of Diaryl Ketones
Jieyu Zhou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Role of Biocatalysis in Sustainable Chemistry
Roger A. Sheldon et al.
CHEMICAL REVIEWS (2018)
Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases
Steven A. Sattler et al.
PLANT PHYSIOLOGY (2017)
Rational design of Kluyveromyces marxianus ZJB14056 aldo-keto reductase KmAKR to enhance diastereoselectivity and activity
Ya-Jun Wang et al.
ENZYME AND MICROBIAL TECHNOLOGY (2017)
Identification of a Robust Carbonyl Reductase for Diastereoselectively Building syn-3,5-Dihydroxy Hexanoate: a Bulky Side Chain of Atorvastatin
Xu-Min Gong et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2017)
Semi-rational engineering of a thermostable aldo-keto reductase from Thermotoga maritima for synthesis of enantiopure ethyl-2-hydroxy-4-phenylbutyrate (EHPB)
Zhiguo Wang et al.
SCIENTIFIC REPORTS (2017)
Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S, 3R, 4S)-4-hydroxyisoleucine with three asymmetric centers
Xuan Shi et al.
SCIENTIFIC REPORTS (2017)
Engineering Streptomyces coelicolor Carbonyl Reductase for Efficient Atorvastatin Precursor Synthesis
Min Li et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2017)
Recent advances in biotechnological applications of alcohol dehydrogenases
Yu-Guo Zheng et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering
Jan-Ytzen van der Meer et al.
CHEMBIOCHEM (2016)
Structure-guided stereoselectivity inversion of a short-chain dehydrogenase/reductase towards halogenated acetophenones
Aipeng Li et al.
CHEMICAL COMMUNICATIONS (2016)
Activity improvement of a Kluyveromyces lactis aldo-keto reductase KlAKR via rational design
Xi Luo et al.
JOURNAL OF BIOTECHNOLOGY (2016)
Engineering of Candida glabrata Ketoreductase 1 for Asymmetric Reduction of α-Halo Ketones
Fengyu Qin et al.
ACS CATALYSIS (2016)
The aldo-keto reductases (AKRs): Overview
Trevor M. Penning
CHEMICO-BIOLOGICAL INTERACTIONS (2015)
Cloning and characterization of a NADH-dependent aldo-keto reductase from a newly isolated Kluyveromyces lactis XP1461
Xi Luo et al.
ENZYME AND MICROBIAL TECHNOLOGY (2015)
Cloning, expression and enzymatic characterization of an aldo-keto reductase from Candida albicans XP1463
Ya-Jun Wang et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2015)
Controlling Substrate Specificity and Stereospecificity of Alcohol Dehydrogenases
Christopher M. Nealon et al.
ACS CATALYSIS (2015)
Semi-Rational Engineering a Carbonyl Reductase for the Enantioselective Reduction of β-Amino Ketones
Dalong Zhang et al.
ACS CATALYSIS (2015)
Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2
Peng-Chao Guo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2014)
Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis
Haiyun Pan et al.
PLANT CELL (2014)
Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones
Henry Man et al.
TOPICS IN CATALYSIS (2014)
Engineering of Flexible Loops in Enzymes
Bettina M. Nestl et al.
ACS CATALYSIS (2014)
Biochemical and structural characterization of recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius highly enantioselective on diaryl diketone benzil
Angela Pennacchio et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
Biocatalytic ketone reduction: A green and efficient access to enantiopure alcohols
Yan Ni et al.
BIOTECHNOLOGY ADVANCES (2012)
Engineering the third wave of biocatalysis
U. T. Bornscheuer et al.
NATURE (2012)
Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans
Xu Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones
Yao Nie et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Recent advances in alcohol dehydrogenase-catalyzed asymmetric production of hydrophobic alcohols
Musa M. Musa et al.
CATALYSIS SCIENCE & TECHNOLOGY (2011)
Practical chiral alcohol manufacture using ketoreductases
Gjalt W. Huisman et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2010)
Structural Insight into Substrate Differentiation of the Sugar-metabolizing Enzyme Galactitol Dehydrogenase from Rhodobacter sphaeroides D
Yvonne Carius et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Highly Enantioselective Mutant Carbonyl Reductases Created via Structure-Based Site-Saturation Mutagenesis
Hongmei Li et al.
JOURNAL OF ORGANIC CHEMISTRY (2010)
How carbonyl reductases control stereoselectivity: Approaching the goal of rational design
Dunming Zhu et al.
PURE AND APPLIED CHEMISTRY (2010)
Structure of D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate D-3-hydroxybutyrate and NAD+
Md Mominul Hoque et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2009)
A Single Point Mutation Reverses the Enantiopreference of Thermoanaerobacter ethanolicus Secondary Alcohol Dehydrogenase
Musa M. Musa et al.
CHEMCATCHEM (2009)
The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes
K. L. Kavanagh et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Inverting the enantioselectivity of a carbonyl reductase via substrate-enzyme docking-guided point mutation
Dunming Zhu et al.
ORGANIC LETTERS (2008)
Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity
Rongzhen Zhang et al.
PROTEIN SCIENCE (2008)
Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the shortchain dehydrogenase/reductase superfamily
Frank Hoffmann et al.
DRUG METABOLISM REVIEWS (2007)
Recent developments in asymmetric reduction of ketones with biocatalysts
K Nakamura et al.
TETRAHEDRON-ASYMMETRY (2003)